Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 |
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
- Biological Evaluation of Molecular Spherical Nucleic Acids: Targeting Tumors via a Hybridization-Based Folate Decoration (2025)
- ACS Omega
- Post-SELEX modification of quinine aptamers through neoacetalization (2025)
- Organic and Biomolecular Chemistry
- The Impact of Secondary Structure on the Base-Filling of N-Methoxy-1,3-Oxazinane (MOANA) and N-Methoxy-1,3-Oxazolidine Glycol Nucleic Acid (MOGNA) Oligonucleotides (2025)
- ChemBioChem
- Chondroitin Sulfate-Coated Heteroduplex-Molecular Spherical Nucleic Acids (2024)
- ChemBioChem
- Probing the nucleobase selectivity of RNA polymerases with dual-coding substrates (2024)
- Journal of Biological Chemistry
- Tuning the Solubility of Soluble Support Constructs in Liquid Phase Oligonucleotide Synthesis (2024)
- Journal of Organic Chemistry
- 5'-O-(2-Isopropoxyprop-2-yl)-protected Phosphoramidite Building Blocks in the Liquid Phase Oligonucleotide Synthesis (2023)
- European Journal of Organic Chemistry
- Assembly of split aptamers by dynamic pH-responsive covalent ligation (2023)
- Chemical Communications
- In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography (2023)
- Molecular Pharmaceutics
- Pretargeted PET imaging of trans-cyclooctene functionalized spherical nucleic acids (2023)
- Nuclear Medicine and Biology
- Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway (2023)
- ACS Chemical Biology
- Stereo-Controlled Liquid Phase Synthesis of Phosphorothioate Oligonucleotides on a Soluble Support (2023)
- Journal of Organic Chemistry
- Synthesis of Site-Specific Antibody-[60]Fullerene-Oligonucleotide Conjugates for Cellular Targeting (2023)
- ACS Applied Bio Materials
- Tetrazine Glycoconjugate for Pretargeted Positron Emission Tomography Imaging of trans-Cyclooctene-Functionalized Molecular Spherical Nucleic Acids (2023)
- ACS Omega
- Watson-Crick Base Pairing of N-Methoxy-1,3-Oxazinane (MOANA) Nucleoside Analogues within Double-Helical DNA (2023)
- ChemistryOpen
- 2-Trifluoromethyl-6-mercurianiline Nucleotide, a Sensitive F-19 NMR Probe for Hg(II)-mediated Base Pairing (2022)
- Journal of Organic Chemistry
- Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids (2022)
- Bioconjugate Chemistry
- DNA-Templated Formation and N,O-Transacetalization of N-Methoxyoxazolidines (2022)
- European Journal of Organic Chemistry
- N-Methoxy-1,3-oxazinane nucleic acids (MOANAs) - a configurationally flexible backbone modification allows post-synthetic incorporation of base moieties (2022)
- Organic and Biomolecular Chemistry
- O-59 - Radiolabeling and biological evaluation of functionalized spherical nucleic acids (2022)
- Nuclear Medicine and Biology