Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6218-2212 |
Areas of expertise
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Publications 
1 of 5
- Biological Evaluation of Molecular Spherical Nucleic Acids: Targeting Tumors via a Hybridization-Based Folate DecorationPost-SELEX modification of quinine aptamers through neoacetalization (2025)
- ACS Omega
(A1 Refereed original research article in a scientific journal) - The Impact of Secondary Structure on the Base-Filling of N-Methoxy-1,3-Oxazinane (MOANA) and N-Methoxy-1,3-Oxazolidine Glycol Nucleic Acid (MOGNA) Oligonucleotides (2025)
- Organic and Biomolecular ChemistryChemBioChem
(A1 Refereed original research article in a scientific journal) - (2025)
(A1 Refereed original research article in a scientific journal) - Chondroitin Sulfate-Coated Heteroduplex-Molecular Spherical Nucleic AcidsProbing the nucleobase selectivity of RNA polymerases with dual-coding substrates (2024)
- ChemBioChem
(A1 Refereed original research article in a scientific journal) - (2024)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - Tuning the Solubility of Soluble Support Constructs in Liquid Phase Oligonucleotide Synthesis (2024)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - 5'-O-(2-Isopropoxyprop-2-yl)-protected Phosphoramidite Building Blocks in the Liquid Phase Oligonucleotide Synthesis (2023)
- European Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Assembly of split aptamers by dynamic pH-responsive covalent ligation (2023)
- Chemical Communications
(A1 Refereed original research article in a scientific journal) - In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography (2023)
- Molecular Pharmaceutics
(A1 Refereed original research article in a scientific journal) - Pretargeted PET imaging of trans-cyclooctene functionalized spherical nucleic acids (2023)
- Nuclear Medicine and Biology
(Other publication) - Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway (2023)
- ACS Chemical Biology
(A1 Refereed original research article in a scientific journal) - Stereo-Controlled Liquid Phase Synthesis of Phosphorothioate Oligonucleotides on a Soluble Support (2023)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Synthesis of Site-Specific Antibody-[60]Fullerene-Oligonucleotide Conjugates for Cellular Targeting (2023)
- ACS Applied Bio Materials
(A1 Refereed original research article in a scientific journal) - Tetrazine Glycoconjugate for Pretargeted Positron Emission Tomography Imaging of trans-Cyclooctene-Functionalized Molecular Spherical Nucleic Acids (2023)
- ACS Omega
(A1 Refereed original research article in a scientific journal) - Watson-Crick Base Pairing of N-Methoxy-1,3-Oxazinane (MOANA) Nucleoside Analogues within Double-Helical DNA (2023)
- ChemistryOpen
(A1 Refereed original research article in a scientific journal) - 2-Trifluoromethyl-6-mercurianiline Nucleotide, a Sensitive F-19 NMR Probe for Hg(II)-mediated Base Pairing (2022)
- Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids (2022)
- Bioconjugate Chemistry
(A1 Refereed original research article in a scientific journal) - DNA-Templated Formation and N,O-Transacetalization of N-Methoxyoxazolidines (2022)
- European Journal of Organic Chemistry
(A1 Refereed original research article in a scientific journal) - N-Methoxy-1,3-oxazinane nucleic acids (MOANAs) - a configurationally flexible backbone modification allows post-synthetic incorporation of base moieties (2022)
- Organic and Biomolecular Chemistry
(A1 Refereed original research article in a scientific journal) - O-59 - Radiolabeling and biological evaluation of functionalized spherical nucleic acids (2022)
- Nuclear Medicine and Biology
(Other publication)
UTU Research Portal