Matej Oresic
Ph.D.
matej.oresic@utu.fi +358 29 450 3798 +358 46 923 3395 Tykistökatu 6 Turku ORCID identifier: https://orcid.org/0000-0002-2856-9165 |
Systems biology, exposome, bioinformatics, metabolomics, lipidomics, biophysics, systems medicine, computational biology
Professor Matej Orešič holds a PhD in biophysics from Cornell University (1999; Ithaca, NY, USA). He is professor of medicine, with specialization in systems medicine at Örebro University (Sweden) and a professor of biochemistry (metabolomics) at the University of Turku (Finland). Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. As of 2016, he was made a Lifetime Honorary Fellow of the Metabolomics Society. Professor Orešič currently serves as member of the Board of Directors of the Metabolomics Society and is one of the founders of the Nordic Metabolomics Society, previously serving as its chair of the board. In 2019, he co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA). Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
Professor Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
- The inflammatory path toward type 1 diabetes begins during pregnancyPerfluorooctanoic acid disrupts hepatic metabolism in the developing chicken embryo (2026)
- Nature CommunicationsMetabolomics
(A1 Refereed original research article in a scientific journal) - Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac diseasePrenatal exposure to perfluoroalkyl substances predicts multimodal brain structural and functional outcomes in children aged 5 years: a birth cohort study (2026)
- BMC MedicineEnvironment International
(A1 Refereed original research article in a scientific journal) - Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial (2025)
- Neuropsychopharmacology
(A1 Refereed original research article in a scientific journal) - Dynamics of gut metabolome and microbiota maturation during early life (2025)
- iScienceThe Lancet Planetary Health
(A1 Refereed original research article in a scientific journal) - Intra- and inter-individual variation of the human lipidomeThe SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research (2025)
- Trends in Analytical ChemistryAnalytical Chemistry
(A2 Refereed review article in a scientific journal ) - Liquid and gas-chromatography-mass spectrometry methods for exposome analysis (2025)
- Journal of Chromatography A
(A2 Refereed review article in a scientific journal ) - Metabolome informs about the chemical exposome and links to brain health (2025)
(A2 Refereed review article in a scientific journal ) - (2025)
(A1 Refereed original research article in a scientific journal) - 2025
(A1 Refereed original research article in a scientific journal) - (2025)
(A1 Refereed original research article in a scientific journal)



