Kalle Rytkönen
Senior Research Fellow, InFLAMES Flagship, Institute of Biomedicine / Turku Bioscience Centre
katury@utu.fi Tykistökatu 6 Turku ORCID identifier: https://orcid.org/0000-0002-5138-0889 |
Female reproduction; reproductive immunology; uterus; endometrium; endometriosis; preeclampsia; hypoxia; gene regulation; functional genomics; single-cell transcriptomics
2011, PhD, University of Turku
2012-2015 Post Doc, Prof. Gunter Wagner lab, Yale Systems Biology Institute, Yale University
2016-2018 Marie Curie Research Fellow, Institute of Biomedicine / Turku Centre for Biotechnology
2019- Research Fellow associated with Prof. Laura Elo and Prof. Matti Poutanen groups, Turku Bioscience Centre / Institute of Biomedicine
2022- Adjunct professor, Institute of Biomedicine
Current research focuses on the gene regulation of the uterine endometrium and endometrium related disorders such as preeclampsia, endometriosis, PCOS and heavy menstrual bleeding. To better understand the uterine biology and the roles of specific uterine cell types I utilize transcriptomics, steroidomics and computational biology tools.
Lectures in courses: Modern biotechnologies and bioinformatics; Systems biology; Bioinformatics in Drug Discovery.
- REACTOR: REgulon Activity analysis and Comparison Tool for single-cell transcriptOmics Research (2026)
- Bioinformatics
(A1 Refereed original research article in a scientific journal) - Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice (2026)
- FASEB Journal
(A1 Refereed original research article in a scientific journal) - Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis (2024)
- FASEB Journal
(A1 Refereed original research article in a scientific journal) - Gene Regulatory Network Analysis of Decidual Stromal Cells and Natural Killer Cells (2024)
- Reproductive Sciences
(A1 Refereed original research article in a scientific journal) - Integrative analysis of endometriosis and adenomyosis through single-cell transcriptomics (2024)
- Human Reproduction
(Abstract) - Serum Hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein a but does not serve as an independent marker for preeclampsia (2024)
- Biology of Reproduction
(A1 Refereed original research article in a scientific journal) - Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in preeclampsia (2022)
- Reproduction
(A1 Refereed original research article in a scientific journal) - COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts (2022)
- Frontiers in Genetics
(A1 Refereed original research article in a scientific journal) - Dirichlet process mixture models for single-cell RNA-seq clustering (2022)
- Biology Open
(A1 Refereed original research article in a scientific journal) - Glycolysis and Heavy Menstrual Bleeding (2022)
- Reproductive Sciences
(B1 Non-refereed article in a scientific journal)
