Olena Parilova
MS
olena.parilova@utu.fi Työhuone: B311 (3 floor) ORCID-tunniste: https://orcid.org/0000-0003-2282-4425 |
Asiantuntijuusalueet
RNA polymerase I; in vitro transcription; protein purification; structural biology
RNA polymerase I; in vitro transcription; protein purification; structural biology
Tutkimus
I focus on the mechanism of transcription initiation by RNA polymerase I (Pol1). I study in vitro reconstituted Pol1 system from Saccharomyces cerevisiae as a model and elucidate its function using single molecule biophysical methods capable of real-time monitoring of proteins.
Julkaisut
- Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway (2022)
- Journal of Molecular Biology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Archaic and alternative chaperones preserve pilin folding energy by providing incomplete structural information (2018)
- Journal of Biological Chemistry
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Structural basis for Acinetobacter baumannii biofilm formation (2018)
- Proceedings of the National Academy of Sciences of the United States of America
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )