Olena Parilova
 MS
| 
 olena.parilova@utu.fi Työhuone: B311 (3 floor) ORCID-tunniste: https://orcid.org/0000-0003-2282-4425 | 
 Asiantuntijuusalueet 
RNA polymerase I; in vitro transcription; protein purification; structural biology
RNA polymerase I; in vitro transcription; protein purification; structural biology
 Tutkimus 
I focus on the mechanism of transcription initiation by RNA polymerase I (Pol1). I study in vitro reconstituted Pol1 system from Saccharomyces cerevisiae as a model and elucidate its function using single molecule biophysical methods capable of real-time monitoring of proteins.
 Julkaisut   
  
            - Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway  (2022)  - Journal of Molecular Biology
 
 (A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Archaic and alternative chaperones preserve pilin folding energy by providing incomplete structural information  (2018)  - Journal of Biological Chemistry
 
 (A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
- Structural basis for Acinetobacter baumannii biofilm formation  (2018)  - Proceedings of the National Academy of Sciences of the United States of America
 
 (A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
