PhD Pekka Rappu - UTU Research Portal

Pekka Rappu
PhD

- University Teacher,
Biochemistry (Department of Life Technologies)
- Docent,
Department of Life Technologies (Faculty of Technology)

pekrappu@utu.fi

+358 29 450 4785

Tykistökatu 6

Turku

: https://orcid.org/0000-0002-5068-2842

Research group: Structure and Function of Collagen Receptor Integrins

Extracellular matrix
Proteomics
Integrins

Solu ja biomolekyylit - käytäntö
Molekyylibiologia - käytäntö

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H-Ras activation and fibroblast-induced TGF-β signaling promote laminin-332 accumulation and invasion in cutaneous squamous cell carcinoma (2020)
- Matrix Biology
Siljamäki E, Rappu P, Riihilä P, Nissinen L, Kähäri VM, Heino J.
Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction (2020)
- Gut
Tulkens Joeri, Vergauwen Glenn, Van Deun Jan, Geeurickx Edward, Dhondt Bert, Lippens Lien, De Scheerder Marie-Angelique, Miinalainen Ilkka, Rappu Pekka, De Geest Bruno G, Vandecasteele Katrien, Laukens Debby, Vandekerckhove Linos, Denys Hannelore, Vandesompele Jo, De Wever Olivier, Hendrix An
Integration of Matrisome Omics: Towards System Biology of the Tumor Matrisome (2020) Extracellular Matrix Omics Valerio Izzi, Jarkko Koivunen, Pekka Rappu, Jyrki Heino, Taina Pihlajaniemi
Interaction between prostate cancer cells and prostate fibroblasts promotes accumulation and proteolytic processing of basement membrane proteins (2020)
- Prostate
Ojalill M, Virtanen N, Rappu P, Siljamäki E, Taimen P, Heino J
Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine (2020)
- Journal of Extracellular Vesicles
Dhondt B, Geeurickx E, Tulkens J, Van Deun J, Vergauwen G, Lippens L, Miinalainen I, Rappu P, Heino J, Ost P, Lumen N, De Wever O, Hendrix A
FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy (2019)
- eLife
Osterman CJD, Ozmadenci D, Kleinschmidt EG, Taylor KN, Barrie AM, Jiang SL, Bean LM, Sulzmaier FJ, Jean C, Tancioni I, Anderson K, Uryu S, Cordasco EA, Li J, Chen XL, Fu G, Ojalill M, Rappu P, Heino J, Mark AM, Xu GR, Fisch KM, Kolev VN, Weaver DT, Pachter JA, Gyorffy B, McHale MT, Connolly DC, Molinolo A, Stupack DG, Schlaepfer DD, Schlaepfer DD
Role of prolyl hydroxylation in the molecular interactions of collagens (2019)
- Essays in Biochemistry
Rappu P., Salo A., Myllyharju J., Heino J.
Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells (2018)
- Oncotarget
Ojalill M., Parikainen M., Rappu P., Aalto E., Jokinen J., Virtanen N., Siljamäki E., Heino J.
Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms (2018)
- Journal of Biological Chemistry
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
- Prostate
Marjaana Ojalill, Pekka Rappu, Elina Siljamäki, Pekka Taimen, Peter Boström, Jyrki Heino