PhD Pekka Rappu - UTU Research Portal

Pekka Rappu
PhD

- University Teacher,
Biochemistry (Department of Life Technologies)
- Docent,
Department of Life Technologies (Faculty of Technology)

pekrappu@utu.fi

+358 29 450 4785

Tykistökatu 6

Turku

: https://orcid.org/0000-0002-5068-2842

Research group: Structure and Function of Collagen Receptor Integrins

Extracellular matrix
Proteomics
Integrins

Solu ja biomolekyylit - käytäntö
Molekyylibiologia - käytäntö

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A living biobank of sarcoma patient-derived cell cultures reveals multi-omic and functional insights that capture disease heterogeneity (2026)
- Clinical and translational medicine
Gijsels, Stefanie; Fischer, Suzanne; Creytens, David; Dedeyne, Sándor; De Vuyst, Felix; Pinheiro, Cláudio; Cordier, Fleur; Bekaert, Sarah-Lee; Van Roy, Nadine; Durinck, Kaat; Pauwels, Jarne; Gevaert, Kris; Mestdagh, Pieter; Vandesompele, Jo; Rappu, Pekka; Heino, Jyrki; Hendrix, An; van Ramshorst, Gabrielle H.; Sys, Gwen; De Wever, Olivier
A One-Step Workflow for Size-Based Separation of Extracellular Vesicles With Integrated Surface Marker Detection (2026)
- Journal of Extracellular Biology
Lippens, Lien; Guilbert, Niké; Van Dorpe, Sofie; Deville, Sarah; Boiy, Robin; Roux, Quentin; Lumen, Nicolaas; Miinalainen, Ilkka; Rappu, Pekka; Vandecasteele, Katrien; Denys, Hannelore; De Geest, Bruno; De Wever, Olivier; Hendrix, An
C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis (2026)
- Oncogenesis
Salmela, Maria; Nissinen, Liisa; Rappu, Pekka; Viiklepp, Kristina; Ojalill, Marjaana; Heino, Jyrki; Riihilä, Pilvi; Kähäri, Veli-Matti
Embigin is involved in the regulation of early mouse kidney development (2026)
- Scientific Reports
Talvi, Salli; Jokinen, Johanna; Rappu, Pekka; Leppäkoski, Roni; Kurtzeborn, Kristen; Rantakari, Pia; Kuure, Satu; Heino, Jyrki
Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer (2026)
- Science Advances
Parikainen, Marjaana; Suwal, Ujjwal; Rappu, Pekka; Heino, Jyrki; Sahlgren, Cecilia M.
P4HA3 is dispensable for prolyl 4-hydroxylation of type I collagen during mouse development (2026)
- Journal of Biological Chemistry
Karjalainen, Emma; Rappu, Pekka; Izzi, Valerio; Miinalainen, Ilkka; Heino, Jyrki; Myllyharju, Johanna; Salo, Antti M.
PI3K and MAPK Signaling Nodes Serve as Divergent Drivers of Phenotypic Plasticity in Cancer-Associated Fibroblasts in Colorectal Cancer (2026)
- Cancer Research
Xia, Zihan; De Vuyst, Felix; Ernst, Sam; Suwal, Ujjwal; Vander Cruyssen, Amélie; Rappu, Pekka; Heino, Jyrki; Dedeyne, Sandor; Ceelen, Wim; Craciun, Ligia; Demetter, Pieter; Hendrix, An; De Wever, Olivier
Expression of C1q by Macrophages and Fibroblasts in Tumor Microenvironment Is Associated with Progression and Metastasis of Cutaneous Squamous Cell Carcinoma (2025)
- Journal of Investigative Dermatology
Viiklepp, Kristina; Knuutila, Jaakko S.; Nissinen, Liisa; Siljamäki, Elina; Rappu, Pekka; Suwal, Ujjwal; Pellinen, Teijo; Kallajoki, Markku; Meri, Seppo; Heino, Jyrki; Kähäri, Veli-Matti; Riihilä, Pilvi
Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids (2025)
- Nature Protocols
Blondeel, Eva; Ernst, Sam; De Vuyst, Felix; Diosdi, Akos; Pinheiro, Claudio; Estevao, Diogo; Rappu, Pekka; Boiy, Robin; Dedeyne, Sandor; Craciun, Ligia; Goossens, Vera; Dehairs, Jonas; Cruz, Tania; Audenaert, Dominique; Ceelen, Wim; Linnebacher, Michael; Boterberg, Tom; Vandesompele, Jo; Mestdagh, Pieter; Swinnen, Johan; Heino, Jyrki; Horvath, Peter; Oliveira, Maria Jose; Hendrix, An; De Metter, Pieter; De Wever, Olivier
Cancer-associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer (2024)
- Clinical and translational medicine
Xia, Zihan; Vermeulen, Stephanie; Suwal, Ujjwal; Rappu, Pekka; Heino, Jyrki; De Vuyst, Felix; Dedeyne, Sandor; Hendrix, An; Denys, Hannelore; De Wever, Olivier