PhD Pekka Rappu - UTU Research Portal

Pekka Rappu
PhD

- University Teacher,
Biochemistry (Department of Life Technologies)
- Docent,
Department of Life Technologies (Faculty of Technology)

pekrappu@utu.fi

+358 29 450 4785

Tykistökatu 6

Turku

ORCID identifier: https://orcid.org/0000-0002-5068-2842

Research group: Structure and Function of Collagen Receptor Integrins

Research

Extracellular matrix
Proteomics
Integrins

Teaching

Solu ja biomolekyylit - käytäntö
Molekyylibiologia - käytäntö

Publications

2 of 2

Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells (2018)
- Oncotarget
Ojalill M., Parikainen M., Rappu P., Aalto E., Jokinen J., Virtanen N., Siljamäki E., Heino J.
(A1 Refereed original research article in a scientific journal)
Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms (2018)
- Journal of Biological Chemistry
Kalle H. Sipilä, Kati Drushinin, Pekka Rappu, Johanna Jokinen, Tiina A. Salminen, Antti M. Salo, Jarmo Käpylä, Johanna Myllyharju, Jyrki Heino
(A1 Refereed original research article in a scientific journal)
The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
- Prostate
Marjaana Ojalill, Pekka Rappu, Elina Siljamäki, Pekka Taimen, Peter Boström, Jyrki Heino
(A1 Refereed original research article in a scientific journal)
Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling (2017)
- Scientific Reports
Salmela Maria, Jokinen Johanna, Tiitta Silja, Rappu Pekka, Cheng Holland R, Heino Jyrki
(A1 Refereed original research article in a scientific journal)
Joint inflammation related citrullination of functional arginines in extracellular proteins (2017)
- Scientific Reports
Sipila KH, Ranga V, Rappu P, Mali M, Pirila L, Heino I, Jokinen J, Kapyla J, Johnson MS, Heino J
(A1 Refereed original research article in a scientific journal)
Extracellular citrullination inhibits the function of matrix associated TGF-beta (2016)
- Matrix Biology
Sipila KH, Ranga V, Rappu P, Torittu A, Pirila L, Kapyla J, Johnson MS, Larjava H, Heino J
(A1 Refereed original research article in a scientific journal)
Platelet response to a small molecule inhibitor of α2β1 integrin is associated with ITGA2 C807T dimorphism. (2016)
- Platelets
Nissinen L, Rappu P, Ollikka P, Nieminen J, Marjamäki A, Heino J
(A1 Refereed original research article in a scientific journal)
Tumor promoter PMA enhances kindlin-2 and decreases vimentin recruitment into cell adhesion sites (2016)
- International Journal of Biochemistry and Cell Biology
Salmela M, Rappu P, Lilja J, Niskanen H, Taipalus E, Jokinen J, Heino J
(A1 Refereed original research article in a scientific journal)
Melanoma-Associated Cancer-Testis Antigen 16 (CT16) Regulates the Expression of Apoptotic and Antiapoptotic Genes and Promotes Cell Survival (2012)
- PLoS ONE
Nylund C, Rappu P, Pakula E, Heino A, Laato L, Elo LL, Vihinen P, Pyrhonen S, Owen GR, Larjava H, Kallajoki M, Heino J
(A1 Refereed original research article in a scientific journal)
Characterization of Intrinsically Disordered Prostate Associated Gene (PAGE5) at Single Residue Resolution by NMR Spectroscopy (2011)
- PLoS ONE
Hellman M, Tossavainen H, Rappu P, Heino J, Permi P
(A1 Refereed original research article in a scientific journal)
Characterization of local structural features of intrinsically disordered cancer-testis antigen (CT16) at single residue resolution by NMR spectroscopy (2011)
- PLoS ONE
Maarit Hellman, Helena Tossavainen, Pekka Rappu, Jyrki Heino, Perttu Permi
(A1 Refereed original research article in a scientific journal)
Detection of melanoma-derived cancer-testis antigen CT16 in patient sera by a novel immunoassay (2011)
- International Journal of Cancer
Rappu P, Nylund C, Ristiniemi N, Kulpakko J, Vihinen P, Hernberg M, Mirtti T, Alanen K, Kallajoki M, Vuoristo MS, Pyrhonen S, Heino J
(A1 Refereed original research article in a scientific journal)
Detection of melanoma-derived cancer-testis antigen CT16 in patient sera by a novel immunoassay (2010)
- Journal of Investigative Dermatology
Rappu P, Nylund C, Ristiniemi N, Kulpakko J, Vihinen P, Hernberg M, Alanen K, Kallajoki M, Pyrhönen S, Heino J
(Other publication)