Cost-effective genome-wide estimation of allele frequencies from pooled DNA in Atlantic salmon (Salmo salar L.)

: Ozerov M, Vasemägi A, Wennevik V, Niemelä E, Prusov S, Kent M, Vähä JP

Publisher: BIOMED CENTRAL LTD

: 2013

: BMC Genomics

: BMC GENOMICS

: ARTN 12

: 14

: 9

: 1471-2164

DOI: https://doi.org/10.1186/1471-2164-14-12

: http://www.biomedcentral.com/1471-2164/14/12

Conclusions: Despite of higher level of variation associated with array replicates compared to pool construction, we suggest that both sources of variation should be taken into account. This study demonstrates that DNA pooling allows fast and high-throughput determination of allele frequencies in Atlantic salmon enabling cost-efficient identification of informative markers for discrimination of populations at various geographical scales, as well as identification of loci controlling ecologically and economically important traits.