Sperm, metabolic memory and echoes from Lamarck



: Crisostomo L, Oliveira PF, Alves MG

Publisher: WILEY

: 2021

: European Journal of Clinical Investigation

: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

: EUR J CLIN INVEST

:  e13492

: 51

: 10

: 5

: 0014-2972

DOI: https://doi.org/10.1111/eci.13492

: https://onlinelibrary.wiley.com/doi/10.1111/eci.13492


  • There is a widespread misconception that only maternal variables affect in utero development.
  • Epigenetic markers carried by the spermatozoon are transmitted to the zygote.
  • Sperm-born epigenetic factors influence in utero development, for various generations.
  • Acquired traits of metabolic disease can be inherited by the offspring via the male gamete.
  • Health assessment of future fathers is essential to predict the offspring's health.

Last updated on 2024-26-11 at 23:41