A2 Refereed review article in a scientific journal
Sperm, metabolic memory and echoes from Lamarck
Authors: Crisostomo L, Oliveira PF, Alves MG
Publisher: WILEY
Publication year: 2021
Journal: European Journal of Clinical Investigation
Journal name in source: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Journal acronym: EUR J CLIN INVEST
Article number: e13492
Volume: 51
Issue: 10
Number of pages: 5
ISSN: 0014-2972
DOI: https://doi.org/10.1111/eci.13492
Web address : https://onlinelibrary.wiley.com/doi/10.1111/eci.13492
Abstract
- There is a widespread misconception that only maternal variables affect in utero development.
- Epigenetic markers carried by the spermatozoon are transmitted to the zygote.
- Sperm-born epigenetic factors influence in utero development, for various generations.
- Acquired traits of metabolic disease can be inherited by the offspring via the male gamete.
- Health assessment of future fathers is essential to predict the offspring's health.
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