A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Sperm, metabolic memory and echoes from Lamarck
Tekijät: Crisostomo L, Oliveira PF, Alves MG
Kustantaja: WILEY
Julkaisuvuosi: 2021
Journal: European Journal of Clinical Investigation
Tietokannassa oleva lehden nimi: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
Lehden akronyymi: EUR J CLIN INVEST
Artikkelin numero: e13492
Vuosikerta: 51
Numero: 10
Sivujen määrä: 5
ISSN: 0014-2972
DOI: https://doi.org/10.1111/eci.13492
Verkko-osoite: https://onlinelibrary.wiley.com/doi/10.1111/eci.13492
Tiivistelmä
- There is a widespread misconception that only maternal variables affect in utero development.
- Epigenetic markers carried by the spermatozoon are transmitted to the zygote.
- Sperm-born epigenetic factors influence in utero development, for various generations.
- Acquired traits of metabolic disease can be inherited by the offspring via the male gamete.
- Health assessment of future fathers is essential to predict the offspring's health.
Ladattava julkaisu This is an electronic reprint of the original article. |