Kari Kopra - UTU Research Portal - UTU Research Portal

Kari Kopra

- Docent,
Department of Chemistry (Faculty of Science)
- University Teacher,
- Academy Research Fellow,
Pharmaseutical Chemistry (Department of Chemistry)

khkopr@utu.fi

: https://orcid.org/0000-0001-7585-6020

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2025
- Journal of Biological ChemistryAnalytica Chimica Acta
Sakari, Moona; Bhadane, Rajendra; Kumar, Sujit; Azevedo, Rita; Malakoutikhah, Morteza; Masoumi, Ahmadreza; Littler, Dene R; Härmä, Harri; Kopra, Kari; Pulliainen, Art To
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)
- Molecular Oncology
Kapp, Jonas N.; Verdurmen, Wouter P. R.; Schaefer, Jonas V.; Kopra, Kari; Nagy‐Davidescu, Gabriela; Richard, Elodie; Nokin, Marie‐Julie; Ernst, Patrick; Tamaskovic, Rastislav; Schwill, Martin; Degen, Ralph; Scholl, Claudia; Santamaria, David; Plückthun, Andreas
Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)
- Scientific Reports
Leini, Renne; Kapp, Jonas; Kopra, Kari; Pantsar, Tatu
Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)
Malakoutikhah, Morteza; Kauppi, Laura; Mäntylä, Kalle; Härmä, Harri; Kopra, Kari
Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)
- Nucleic Acids Research
Gooran, Negin; Borsa, Baris A; Hernandez, Frank J; Härmä, Harri; Kopra, Kari
(2024)
- ACS Chemical Biology
Mahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Härmä, Harri; Pantsar, Tatu; Kopra, Kari
Fluorescence-Based Protein Stability Monitoring : A Review (2024)
- International Journal of Molecular Sciences
Gooran Negin, Kopra Kari
(2024)
- Cell Reports Physical Science
Macchia, Eleonora; Björkström, Kim; Tewari, Amit; Eskonen, Ville; Luukkonen, Axel; Ghafari, Amir Mohammad; Sarcina, Lucia; Caputo, Mariapia; Tong-Ochoa, Natalia; Kopra, Kari; Pettersson, Fredrik; Gounani, Zahra; Torsi, Luisa; Härmä, Harri; Österbacka, Ronald
2024
- Methods in Molecular Biology
KRAS : Methods and Protocols Kopra Kari
Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc GTP&ATP assay (2023)
- Analytical and Bioanalytical Chemistry
Kopra Kari, Mahran Randa, Yli-Hollo Titta, Tabata Sho, Vuorinen Emmiliisa, Fujii Yuki, Vuorinen Iida, Ogawa-Iio Aki, Hirayama Akiyoshi, Soga Tomoyoshi, Sasaki Atsuo T, Härmä Harri
(2023)
- Scientific Reports
Mahran Randa, Vello Niklas, Komulainen Anita, Malakoutikhah Morteza, Härmä Harri, Kopra Kari
(2023)
- Analytical Chemistry
Malakoutikhah Morteza, Mahran Randa, Gooran Negin, Masoumi Ahmadreza, Lundell Katri, Liljeblad Arto, Guiley Keelan, Dai Shizhong, Zheng Qinheng, Zhu Lawrence, Shokat Kevan M., Kopra Kari, Härmä Harri
(2022)
- Anticancer Research
Ecke Thorsten H, Scislowski Mikolaj, Hassan Nazia, Saura Mari, Hallmann Steffen, Koch Stefan, Vuolle Sari, Malakoutikhah Morteza, Kopra Kari, Härmä Harri
Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence (2022)
- Analytical and Bioanalytical ChemistryAnalytical Chemistry
Kopra Kari, Hassan Nazia, Vuorinen Emmiliisa, Valtonen Salla, Mahran Randa, Habib Huda, Jalkanen Pinja, Susi Petri, Hytönen Vesa, Hankaniemi Minna, Ylä-Herttuala Seppo, Kakkola Laura, Peurla Markus, Härmä Harri
(2022)
- International Journal of Molecular SciencesScientific Reports
Kopra Kari, Valtonen Salla, Mahran Randa, Kapp Jonas N, Hassan Nazia, Gillette William, Dennis Bryce, Li Lianbo, Westover Kenneth D, Plückthun Andreas, Härmä Harri
Methods to Monitor Ras Activation State (2021) Ras Activity and Signaling: Methods and Protocols Kopra Kari, Härmä Harri
Protease substrate‐independent universal assay for monitoring digestion of native unmodified proteins (2021)
- International Journal of Molecular Sciences
Vuorinen Emmiliisa, Valtonen Salla, Hassan Nazia, Mahran Randa, Habib Huda, Malakoutikhah Morteza, Kopra Kari, Härmä, Harri
Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies (2021)
- mAbs
Valtonen Salla, Vuorinen Emmiliisa, Eskonen Ville, Malakoutikhah Morteza, Kopra Kari, Härmä Harri
Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring (2020)
Kari Kopra, Emmiliisa Vuorinen, Maria Abreu-Blanco, Qi Wang, Ville Eskonen, William Gillette, Arto T. Pulliainen, Matthew Holderfield, Harri Härmä
Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases (2020)
Kari Kopra, Iraida Sharina, Emil Martin, Harri Härmä