Kari Kopra
khkopr@utu.fi |
- ADP-ribosyltransferase-based biocatalysis of non-hydrolyzable NAD+ analogs (2025)
- Journal of Biological Chemistry
- A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)
- Molecular Oncology
- Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)
- Scientific Reports
- Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)
- Analytica Chimica Acta
- Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)
- Nucleic Acids Research
- Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 (2024)
- ACS Chemical Biology
- Fluorescence-Based Protein Stability Monitoring : A Review (2024)
- International Journal of Molecular Sciences
- Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit (2024)
- Cell Reports Physical Science
- Luminescence-Based Techniques for KRAS Thermal Stability Monitoring (2024)
- Methods in Molecular Biology
- Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc GTP&ATP assay (2023)
- Analytical and Bioanalytical Chemistry
- Isothermal chemical denaturation assay for monitoring protein stability and inhibitor interactions (2023)
- Scientific Reports
- Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes (2023)
- Analytical Chemistry
- Luminophore Chemistry for Detection of Urinary Bladder Cancer - Comparison to Cytology and Urinary Rapid Tests (BTA stat®, NMP22® BladderChek® and UBC® Rapid Test) (2022)
- Anticancer Research
- Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence (2022)
- Analytical and Bioanalytical Chemistry
- Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability (2022)
- International Journal of Molecular Sciences
- Methods to Monitor Ras Activation State (2021) Ras Activity and Signaling: Methods and Protocols Kopra Kari, Härmä Harri
- Protease substrate‐independent universal assay for monitoring digestion of native unmodified proteins (2021)
- International Journal of Molecular Sciences
- Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies (2021)
- mAbs
- Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring (2020)
- Analytical Chemistry
- Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases (2020)
- Scientific Reports