Kari Kopra - UTU Research Portal - UTU Research Portal

Kari Kopra

- Docent,
Department of Chemistry (Faculty of Science)
- University Teacher,
Pharmaseutical Chemistry (Department of Chemistry)

khkopr@utu.fi

ORCID identifier: https://orcid.org/0000-0001-7585-6020

Publications

1 of 5

ADP-ribosyltransferase-based biocatalysis of non-hydrolyzable NAD+ analogs (2025)
- Journal of Biological Chemistry
Sakari, Moona; Bhadane, Rajendra; Kumar, Sujit; Azevedo, Rita; Malakoutikhah, Morteza; Masoumi, Ahmadreza; Littler, Dene R; Härmä, Harri; Kopra, Kari; Pulliainen, Art To
(A1 Refereed original research article in a scientific journal)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)
- Molecular Oncology
Kapp, Jonas N.; Verdurmen, Wouter P. R.; Schaefer, Jonas V.; Kopra, Kari; Nagy‐Davidescu, Gabriela; Richard, Elodie; Nokin, Marie‐Julie; Ernst, Patrick; Tamaskovic, Rastislav; Schwill, Martin; Degen, Ralph; Scholl, Claudia; Santamaria, David; Plückthun, Andreas
(A1 Refereed original research article in a scientific journal)
Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)
- Scientific Reports
Leini, Renne; Kapp, Jonas; Kopra, Kari; Pantsar, Tatu
(A1 Refereed original research article in a scientific journal)
Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)
- Analytica Chimica Acta
Malakoutikhah, Morteza; Kauppi, Laura; Mäntylä, Kalle; Härmä, Harri; Kopra, Kari
(A1 Refereed original research article in a scientific journal)
Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)
- Nucleic Acids Research
Gooran, Negin; Borsa, Baris A; Hernandez, Frank J; Härmä, Harri; Kopra, Kari
(A1 Refereed original research article in a scientific journal)
Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 (2024)
- ACS Chemical Biology
Mahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Härmä, Harri; Pantsar, Tatu; Kopra, Kari
(A1 Refereed original research article in a scientific journal)
Fluorescence-Based Protein Stability Monitoring : A Review (2024)
- International Journal of Molecular Sciences
Gooran, Negin; Kopra, Kari
(A2 Refereed review article in a scientific journal )
Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit (2024)
- Cell Reports Physical Science
Macchia, Eleonora; Björkström, Kim; Tewari, Amit; Eskonen, Ville; Luukkonen, Axel; Ghafari, Amir Mohammad; Sarcina, Lucia; Caputo, Mariapia; Tong-Ochoa, Natalia; Kopra, Kari; Pettersson, Fredrik; Gounani, Zahra; Torsi, Luisa; Härmä, Harri; Österbacka, Ronald
(A1 Refereed original research article in a scientific journal)
Luminescence-Based Techniques for KRAS Thermal Stability Monitoring (2024)
- Methods in Molecular Biology
KRAS : Methods and Protocols Kopra, Kari
(A3 Refereed book chapter or chapter in a compilation book)
Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc GTP&ATP assay (2023)
- Analytical and Bioanalytical Chemistry
Kopra Kari, Mahran Randa, Yli-Hollo Titta, Tabata Sho, Vuorinen Emmiliisa, Fujii Yuki, Vuorinen Iida, Ogawa-Iio Aki, Hirayama Akiyoshi, Soga Tomoyoshi, Sasaki Atsuo T, Härmä Harri
(A1 Refereed original research article in a scientific journal)