Kari Kopra
khkopr@utu.fi ORCID identifier: https://orcid.org/0000-0001-7585-6020 |
Publications 
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- ADP-ribosyltransferase-based biocatalysis of non-hydrolyzable NAD+ analogs (2025)
- Journal of Biological Chemistry
(A1 Refereed original research article in a scientific journal) - A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)
- Molecular Oncology
(A1 Refereed original research article in a scientific journal) - Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)
- Analytica Chimica Acta
(A1 Refereed original research article in a scientific journal) - Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)
- Nucleic Acids Research
(A1 Refereed original research article in a scientific journal) - Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 (2024)
- ACS Chemical Biology
(A1 Refereed original research article in a scientific journal) - Fluorescence-Based Protein Stability Monitoring : A Review (2024)
- International Journal of Molecular Sciences
(A2 Refereed review article in a scientific journal ) - Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit (2024)
- Cell Reports Physical Science
(A1 Refereed original research article in a scientific journal) - Luminescence-Based Techniques for KRAS Thermal Stability Monitoring (2024)
- Methods in Molecular Biology
(A3 Refereed book chapter or chapter in a compilation book) - Homogeneous luminescent quantitation of cellular guanosine and adenosine triphosphates (GTP and ATP) using QT-Luc GTP&ATP assay (2023)
- Analytical and Bioanalytical Chemistry
(A1 Refereed original research article in a scientific journal) - Isothermal chemical denaturation assay for monitoring protein stability and inhibitor interactions (2023)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes (2023)
- Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - Luminophore Chemistry for Detection of Urinary Bladder Cancer - Comparison to Cytology and Urinary Rapid Tests (BTA stat®, NMP22® BladderChek® and UBC® Rapid Test) (2022)
- Anticancer Research
(A1 Refereed original research article in a scientific journal) - Rapid high-throughput compatible label-free virus particle quantification method based on time-resolved luminescence (2022)
- Analytical and Bioanalytical Chemistry
(A1 Refereed original research article in a scientific journal) - Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability (2022)
- International Journal of Molecular Sciences
(A1 Refereed original research article in a scientific journal) - Methods to Monitor Ras Activation State (2021) Ras Activity and Signaling: Methods and Protocols Kopra Kari, Härmä Harri
(A3 Refereed book chapter or chapter in a compilation book) - Protease substrate‐independent universal assay for monitoring digestion of native unmodified proteins (2021)
- International Journal of Molecular Sciences
(A1 Refereed original research article in a scientific journal) - Sensitive, homogeneous, and label-free protein-probe assay for antibody aggregation and thermal stability studies (2021)
- mAbs
(A1 Refereed original research article in a scientific journal) - Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring (2020)
- Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases (2020)
- Scientific Reports
(A1 Refereed original research article in a scientific journal)
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