Kari Kopra - UTU Research Portal - UTU Research Portal

Kari Kopra

- Docent,
Department of Chemistry (Faculty of Science)
- University Teacher,
Pharmaseutical Chemistry (Department of Chemistry)

khkopr@utu.fi

ORCID identifier: https://orcid.org/0000-0001-7585-6020

Publications

2 of 3

Nanomolar Protein-Protein Interaction Monitoring with a Label-Free Protein-Probe Technique (2020)
- Analytical Chemistry
Valtonen S, Vuorinen E, Kariniemi T, Eskonen V, Le Quesne J, Bushell M, Härmä H, Kopra K
(A1 Refereed original research article in a scientific journal)
Sensitive Label-Free Thermal Stability Assay for Protein Denaturation and Protein-Ligand Interaction Studies (2020)
- Analytical Chemistry
Emmiliisa Vuorinen, Salla Valtonen, Ville Eskonen, Taru Kariniemi, Jelena Jakovleva, Kari Kopra, Harri Härmä
(A1 Refereed original research article in a scientific journal)
Single-Peptide TR-FRET Detection Platform for Cysteine-Specific Post-Translational Modifications (2020)
- Analytical Chemistry
Eskonen V, Tong-Ochoa N, Mattsson L, Miettinen M, Lastusaari M, Pulliainen AT, Kopra K, Härmä H
(A1 Refereed original research article in a scientific journal)
eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′UTR (2019)
- Genome Biology
Ania Wilczynska, Sarah L. Gillen, Tobias Schmidt, Hedda A. Meijer, Rebekah Jukes-Jones, Claudia Langlais, Kari Kopra, Wei-Ting Lu, Jack D. Godfrey, Benjamin R. Hawley, Kelly Hodge, Sara Zanivan, Kelvin Cain, John Le Quesne, Martin Bushell
(A1 Refereed original research article in a scientific journal)
High-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors (2019)
- Analytical Biochemistry
Manoharan G.B., Kopra K., Eskonen V., Härmä H., Abankwa D.
(A1 Refereed original research article in a scientific journal)
Homogeneous peptide-break assay for luminescent detection of enzymatic protein post-translational modification activity utilizing charged peptides (2019)
- Analytica Chimica Acta
Kopra K., Tong-Ochoa N., Laine M., Eskonen V., Koskinen P., Härmä H.
(A1 Refereed original research article in a scientific journal)
Peptic Fluorescent "Signal-On" and "Signal-Off" Sensors Utilized for the Detection Protein Post-Translational Modifications (2019)
- ACS Omega
Kopra K, Eskonen V, Seppala T, Jakovleva J, Huttunen R, Harma H
(A1 Refereed original research article in a scientific journal)
QTR-FRET: Efficient background reduction technology in time-resolved förster resonance energy transfer assays (2019)
- Analytica Chimica Acta
Markku Syrjänpää, Emmiliisa Vuorinen, Sakari Kulmala, Qi Wang, Harri Härmä, Kari Kopra
(A1 Refereed original research article in a scientific journal)
Thermal Dissociation Assay for Time-Resolved Fluorescence Detection of Protein Post-Translational Modifications (2019)
- ACS Omega
Ville Eskonen, Natalia Tong-Ochoa, Salla Valtonen, Kari Kopra, Harri Härmä
(A1 Refereed original research article in a scientific journal)
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content (2018)
- Sensors
Kopra K., Seppälä T., Rabara D., Abreu-Blanco M., Kulmala S., Holderfield M., Härmä H.
(A1 Refereed original research article in a scientific journal)
Toward universal protein post-translational modification detection in high throughput format (2018)
- Chemical Communications
Harri Härmä, Natalia Tong-Ochoa, Arjan J. van Adrichem, Ilian Jelesarov, Krister Wennerberg, Kari Kopra
(A1 Refereed original research article in a scientific journal)
High-Throughput Dual Screening Method for Ras Activities and Inhibitors (2017)
- Analytical Chemistry
Kari Kopra, Arjan J. van Adrichem, Outi M. H. Salo-Ahen, Juha Peltonen, Krister Wennerberg, Harri Härmä
(A1 Refereed original research article in a scientific journal)
From Unspecific Quenching to Specific Signaling: Functional GTPase Assays Utilizing Quenching Resonance Energy Transfer (QRET) Technology (2015) Kopra Kari
(G5 Article dissertation )
GTP-Specific Fab Fragment-Based GTPase Activity Assay (2015)
- Analytical Chemistry
Kopra K, Rozwandowicz-Jansen A, Syrjanpaa M, Blazevits O, Ligabue A, Veltel S, Lamminmaki U, Abankwa D, Harma H
(A1 Refereed original research article in a scientific journal)
Homogeneous single-label tyrosine kinase activity assay for high throughput screening (2015)
- Analytica Chimica Acta
Natalia Tong-Ochoa, Kari Kopra, Markku Syrjänpää, Nicolas Legrand, Harri Härmä
(A1 Refereed original research article in a scientific journal)
Quenching resonance energy transfer (QRET): a single-label technique for inhibitor screening and interaction studies (2015)
- New Biotechnology
Kopra Kari, Härmä Harri
(A2 Refereed review article in a scientific journal )
Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation (2015)
- eLife
Maja Šolman, Alessio Ligabue, Olga Blaževitš, Alok Jaiswal, Yong Zhou, Hong Liang, Benoit Lectez, Kari Kopra, Camilo Guzmán, Harri Härmä, John F Hancock, Tero Aittokallio, Daniel Abankwa
(A1 Refereed original research article in a scientific journal)
Time-resolved fluorescence-based assay for rapid detection of Escherichia coli. (2015)
- Analytical Biochemistry
Janne Kulpakko, Kari Kopra, Pekka Hänninen
(A1 Refereed original research article in a scientific journal)
A homogeneous quenching resonance energy transfer assay for H-Ras activation cycle monitoring and inhibitor screening (2014)
- New Biotechnology
Kari Kopra, Arjan van Aldrichem, Markku Syrjänpää, Stefan Veltel, Pekka Hänninen, Daniel Abankwa, Urpo Lamminmäki, Harri Härmä
(Other publication)
A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. (2014)
- Analytical and Bioanalytical Chemistry
Kari Kopra, Alessio Ligabue, Qi Wang, Markku Syrjänpää, Olga Blaževitš,
Stefan Veltel, Arjan J. van Adrichem, Pekka Hänninen, Daniel Abankwa, Harri Härmä
(A1 Refereed original research article in a scientific journal)