Mikko Metsä-Ketelä
mianme@utu.fi +358 29 450 4786 +358 50 436 6523 Tykistökatu 6 Turku |
Natural products; Streptomyces; biosynthesis
http://abelab.utu.fi
Molecular Biology
Structural Biology
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- Molecular evolution of the bacterial pseudouridine-5'-phosphate glycosidase protein family (2014)
- FEBS Journal
- Structure-Based Engineering of Angucyclinone 6-Ketoreductases. (2014)
- Chemistry and Biology
- Biosynthesis of pyranonaphthoquinone polyketides reveals diverse strategies for enzymatic carbon-carbon bond formation (2013)
- Current Opinion in Chemical Biology
- Biosynthetic Conclusions from the Functional Dissection of Oxygenases for Biosynthesis of Actinorhodin and Related Streptomyces Antibiotics (2013)
- Chemistry and Biology
- Chemoenzymatic Synthesis of Novel C-Ribosylated Naphthoquinones (2013)
- ACS Chemical Biology
- Structural and Functional Analysis of Angucycline C-6 Ketoreductase LanV Involved in Landomycin Biosynthesis (2013)
- Biochemistry
- Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway (2013)
- Proceedings of the National Academy of Sciences of the United States of America
- Synthetic Remodeling of the Chartreusin Pathway to Tune Antiproliferative and Antibacterial Activities (2013) Ueberschaar N, Xu ZL, Scherlach K, Metsa-Ketela M, Bretschneider T, Dahse HM, Gorls H, Hertweck C
- Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE (2013)
- Biochemistry
- Alnumycins A2 and A3: new inverse-epimeric pairs stereoisomeric to alnumycin A1 (2012)
- Tetrahedron: Asymmetry
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