PhD Harri Savilahti - UTU Research Portal

Harri Savilahti
PhD

- Professor,
Physiology and Genetics (Department of Biology)

harri.savilahti@utu.fi

+358 40 708 5795

Vesilinnantie 5

Turku

: https://orcid.org/https://orcid.org/0000-0002-6246-2572

Research page

Molecular genetics; DNA transposition technology;

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Two distinct regions in the model protein Peb1 are critical for its heterologous transport out of Escherichia coli (2010)
- Microbial Cell Factories
Anton L, Majander K, Savilahti H, Laakkonen L, Westerlund-Wikstrom B
Universal platform for quantitative analysis of DNA transposition (2010)
- Mobile DNA
Pajunen MI, Rasila TS, Happonen LJ, Lamberg A, Haapa-Paananen S, Kiljunen S, Savilahti H
Application of Mu in vitro transposition for high-precision mapping of protein-protein interfaces on a yeast two-hybrid platform (2009)
- Methods
Pajunen M, Poussu E, Turakainen H, Savilahti H
Critical evaluation of random mutagenesis by error-prone polymerase chain reaction protocols, Escherichia coli mutator strain, and hydroxylamine treatment (2009)
- Analytical Biochemistry
Rasila TS, Pajunen MI, Savilahti H
Generation of Single-Copy Transposon Insertions in Clostridium perfringens by Electroporation of Phage Mu DNA Transposition Complexes (2009)
- Applied and Environmental Microbiology
Lanckriet A, Timbermont L, Happonen LJ, Pajunen MI, Pasmans F, Haesebrouck F, Ducatelle R, Savilahti H, Van Immerseel F
Mu transposition complex mutagenesis in Lactococcus lactis- identification of genes affecting nisin production (2009)
- Journal of Applied Microbiology
Wu Z, Xuanyuan Z, Li R, Jiang D, Li C, Xu H, Bai Y, Zhang X, Turakainen H, Saris PEJ, Savilahti H, Qiao M
Transposition-Based Method for the Rapid Generation of Gene-Targeting Vectors to Produce Cre/Flp-Modifiable Conditional Knock-Out Mice (2009)
- PLoS ONE
Turakainen H, Saarimäki-Vire J, Sinjushina N, Partanen J, Savilahti H
Bacteriophage Mu integration in yeast and mammalian genomes (2008)
- Nucleic Acids Research
Paatero AO, Turakainen H, Happonen LJ, Olsson C, Palomäki T, Pajunen MI, Meng XJ, Otonkoski T, Tuuri T, Berry C, Malani N, Frilander MJ, Bushman FD, Savilahti H
High-precision mapping of protein-protein interfaces: an integrated genetic strategy combining en masse mutagenesis and DNA-level parallel analysis on a yeast two-hybrid platform (2007)
- Nucleic Acids Research
Pajunen M, Turakainen H, Poussu E, Peränen J, Vihinen M, Savilahti H
Isolation and characterization of biofilm formation-defective mutants of Staphylococcus aureus (2007)
- Infection and Immunity
Quoc PHT, Genevaux P, Pajunen M, Savilahti H, Georgopoulos C, Schrenzel J, Kelley WL
SNP discovery by mismatch-targeting of Mu transposition (2007)
- Nucleic Acids Research
Orsini L, Pajunen M, Hanski I, Savilahti H
Characteristics of MuA transposase-catalyzed processing of model transposon end DNA hairpin substrates (2006)
- Nucleic Acids Research
Saarlaho AH, Savilahti H
Genome characterization of lipid-containing marine bacteriophage PM2 by transposon insertion mutagenesis (2006)
- Journal of Virology
Krupovic M, Vilen H, Bamford JKH, Kivelä HM, Aalto JM, Savilahti H, Bamford DH
Actin-organising properties of the muscular dystrophy protein myotilin (2005)
- Experimental Cell Research
von Nandelstadh P, Grönholm M, Moza M, Lamberg A, Savilahti H, Carpen O
A gene truncation strategy generating N- and C-terminal deletion variants of proteins for functional studies: mapping of the Sec1p binding domain in yeast Mso1p by a Mu in vitro transposition-based approach (2005)
- Nucleic Acids Research
Poussu E, Jäntti J, Savilahti H
Behavioural phenotypes of hypomorphic KCC2-deficient mice (2005)
- European Journal of Neuroscience
Tornberg J, Voikar V, Savilahti H, Rauvala H, Airaksinen MS
Functional comparison of the transposition core machineries of phage Mu and Haemophilus influenzae Mu-like prophage Hin-Mu reveals interchangeable components (2005)
- Virology
Saariaho AH, Lamberg A, Elo S, Savilahti H
Meox1(Cre): A mouse line expressing cre recombinase in somitic mesoderm (2005)
- genesis
Jukkola T, Trokovic R, Maj P, Lamberg A, Mankoo B, Pachnis V, Savilahti H, Partanen J
Nonessential genes of phage phi YeO3-12 include genes involved in adaptation to growth on Yersinia enterocolitica serotype O : 3 (2005)
- Journal of Bacteriology
Kiljunen S, Vilen H, Pajunen M, Savilahti H, Skurnik M
Novel mutants of Erwinia carotovora subsp carotovora defective in the production of plant cell wall degrading enzymes generated by Mu transpososome-mediated insertion mutagenesis (2005)
- FEMS Microbiology Letters
Laasik E, Ojarand M, Pajunen M, Savilahti H, Mäe A