PhD Harri Savilahti - UTU Tutkimustietojärjestelmä

Harri Savilahti
PhD

- Professor,
Physiology and Genetics (Department of Biology)

harri.savilahti@utu.fi

+358 40 708 5795

Vesilinnantie 5

Turku

ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6246-2572

Research page

Areas of expertise

Molecular genetics; DNA transposition technology;

Publications

1 of 2

Petter Erik Portin 1940-2023 (2023)
- Turun Sanomat
Nokkala Christina, Savilahti Harri, Vuorisalo Timo
(Other publication)
Petter Portin 1940-2023 (2023)
- Helsingin Sanomat
Nokkala Christina, Savilahti Harri, Vuorisalo Timo
(E1 Popularised article)
The C-terminal region of phytoene synthase is a key element to control carotenoid biosynthesis in the haloarchaeon Haloferax volcanii (2022)
- Biochemical Journal
Cerletti Micaela, Rabino Agustin, Paggi Roberto A, Ferrari Celeste, Poetsch Ansgar, Savilahti Harri, Kiljunen Saija, De Castro Rosana E
(A1 Refereed original research article in a scientific journal)
A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction (2021)
- Nature Communications
Ho Trevor Y. H., Shao Alexander, Lu Zeyu, Savilahti Harri, Menolascina Filippo, Wang Lei, Dalchau Neil, Wang Baojun
(A1 Refereed original research article in a scientific journal)
Intein-assisted bisection mapping systematically splits proteins for Boolean logic and inducibility engineering (2020)
- bioRxiv
Trevor Y. H. Ho, Alexander Shao, Zeyu Lu, Harri Savilahti, Filippo Menolascina, Lei Wang, Neil Dalchau, Baojun Wang
(Other publication)
Applications of the bacteriophage Mu in vitro transposition reaction and genome manipulation via electroporation of DNA transposition complexes (2018) Bacteriophages: Methods and Protocols, Volume 3 Saija Haapa-Paananen, Harri Savilahti
(A3 Refereed book chapter or chapter in a compilation book)
Molecular Factors of Hypochlorite Tolerance in the Hypersaline Archaeon Haloferax volcanii (2018)
- Genes
Gomez M., Leung W., Dantuluri S., Pillai A., Gani Z., Hwang S., McMillan L.J., Kiljunen S., Savilahti H., Maupin-Furlow J.A.
(A1 Refereed original research article in a scientific journal)
Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering (2018)
- Nucleic Acids Research
Tiina S. Rasila, Elsi Pulkkinen, Saija Kiljunen, Saija Haapa-Paananen, Maria I. Pajunen, Anu Salminen, Lars Paulin, Mauno Vihinen, Phoebe A. Rice, Harri Savilahti
(A1 Refereed original research article in a scientific journal)
Transposon Insertion Mutagenesis for Archaeal Gene Discovery (2017) In Vitro Mutagenesis - Methods and Protocols Kiljunen Saija, Pajunen Maria, Savilahti Harri
(A3 Refereed book chapter or chapter in a compilation book)
A set of mini-Mu transposons for versatile cloning of circular DNA and novel dual-transposon strategy for increased efficiency (2016)
- Plasmid
Pulkkinen E, Haapa-Paananen S, Turakainen H, Savilahti H
(A1 Refereed original research article in a scientific journal)
MuA-mediated in vitro cloning of circular DNA: transpositional autointegration and the effect of MuB (2016)
- Molecular Genetics and Genomics
Pulkkinen E, Haapa-Paananen S, Savilahti H
(A1 Refereed original research article in a scientific journal)
Screening of a Haloferax volcanii Transposon Library Reveals Novel Motility and Adhesion Mutants (2016)
- Life
Legerme Georgio, Yang Evan, Esquivel Rianne N, Kiljunen Saija, Savilahti Harri, Pohlschroder Metchild
(A1 Refereed original research article in a scientific journal)
An assay to monitor the activity of DNA transposition complexes yields a general quality control measure for transpositional recombination reactions (2014)
- Mobile Genetic Elements
Elsi Pulkkinen, Saija Haapa-Paananen, Harri Savilahti
(A1 Refereed original research article in a scientific journal)
Generation of comprehensive transposon insertion mutant library for the model archaeon, Haloferax volcanii, and its use for gene discovery (2014)
- BMC Biology
Saija Kiljunen, Maria I Pajunen, Kieran Dilks, Stefanie Storf, Mechthild Pohlschroder, Harri Savilahti
(A1 Refereed original research article in a scientific journal)
Phylogenetic analysis of Maverick/Polinton giant transposons across organisms (2014)
- Molecular Phylogenetics and Evolution
Haapa-Paananen S, Wahlberg N, Savilahti H
(A1 Refereed original research article in a scientific journal)
Flexibility in MuA Transposase Family Protein Structures: Functional Mapping with Scanning Mutagenesis and Sequence Alignment of Protein Homologues (2012)
- PLoS ONE
Rasila TS, Vihinen M, Paulin L, Haapa-Paananen S, Savilahti H
(A1 Refereed original research article in a scientific journal)
A method to sequence and quantify DNA integration for monitoring outcome in gene therapy (2011)
- Nucleic Acids Research
Brady T, Roth SL, Malani N, Wang GP, Berry CC, Leboulch P, Hacein-Bey-Abina S, Cavazzana-Calvo M, Papapetrou EP, Sadelain M, Savilahti H, Bushman FD
(A1 Refereed original research article in a scientific journal)
Boundary cell specific adhesion molecule, PB-cadherin, is not required for maintenance the midbrain-hindbrain border (2010)
- International Journal of Developmental Neuroscience
Saarimaki-Vire J, Turakainen H, Alitalo A, Sinjushina N, Savilahti H, Partanen J
(Other publication)
Genetic recombination pathways and their application for genome modification of human embryonic stem cells (2010)
- Experimental Cell Research
Nieminen M, Tuuri T, Savilahti H
(A2 Refereed review article in a scientific journal )
Mso1p Regulates Membrane Fusion through Interactions with the Putative N-Peptide-binding Area in Sec1p Domain 1 (2010)
- Molecular Biology of the Cell
Weber M, Chernov K, Turakainen H, Wohlfahrt G, Pajunen M, Savilahti H, Jantti J
(A1 Refereed original research article in a scientific journal)