Jarmo Niemi
Ph.D.
jarnie@utu.fi +358 29 450 4701 +358 50 470 4758 Tykistökatu 6 Turku : B6130 |
Antibiotic biosynthesis; biology of Streptomyces; protein research
I started work with antibiotic biosynthesis in 1985, when I worked
for the Finnish pharmaceutical company Leiras, and have continued it
since, except for 1995-1998, when I worked in a project concerning
high-throughput screening methods for peptide receptor agonists.
My Ph. D. thesis in 1995 was about "Hybrid
Anthracycline Antibiotics: Analysis and
Application
of Rhodomycin Biosynthetic Genes from Streptomyces purpurascens".
My
research has concerned the biosynthesis of antibiotics by Streptomyces,
its molecular biology, enzymology and structural biology. I continue to
participate in the research of the "Antibiotic biosynthesis
engineering" group http://abelab.utu.fi/
I teach several initial level Biochemistry courses at the University of Turku; BKEM5030 Cell and Biomolecules - Theory, BKEM5010 Microbiology - Theory, BKEM5011 Microbiology - Practice and part of BKEM5160 Cell and Energy - Theory and BKEM5161 Cell and Energy - Practice.
I also teach the course BJ01A1060 Basic Biochemistry at the Lappeenranta University of Technology.
- Crystal Structure of the Cofactor-Independent Monooxygenase SnoaB from Streptomyces nogalater: Implications for the Reaction Mechanism (2010)
- Biochemistry
- Formation and hydrolysis of amide bonds by lipase A from Candida antarctica; exceptional features (2010)
- Organic and Biomolecular Chemistry
- Structural Basis for Substrate Recognition and Specificity in Aklavinone-11-Hydroxylase from Rhodomycin Biosynthesis (2009)
- Journal of Molecular Biology