Pekka Taimen
MD, PhD
pepeta@utu.fi +358 29 450 4524 +358 50 431 1353 Kiinamyllynkatu 10 Turku Työhuone: D5019 ORCID-tunniste: https://orcid.org/0000-0001-8849-4604 Official web page of research group |
pathology; histology; cell biology; prostate cancer, bladder cancer, cardiomyopathy, nuclear lamin
Pekka Taimen received his MD degree from the University of Turku in 2001 and defended his thesis at the Department of Pathology, University of Turku in 2004. In 2008-2009 PT worked as a postdoctoral fellow in the laboratory of Prof. Robert D. Goldman, Northwestern University Medical School, Chicago. Postdoctoral studies focusing on nuclear intermediate filament proteins called lamins were further continued as a junior group leader after returning back to Turku in early 2010. In 2011 PT received a specialist degree in Pathology and since then he has worked as a part-time specialist at the Pathology Division, Turku University Hospital with special focus on uropathology. From 2012 PT has worked as a Clinical lecturer in Pathology and between 2015-2019 as a part-time Academy of Finland Clinical Researcher. PT was appointed as a tenure track Assistant Professor of Molecular Pathology in January 2019 and an Associate Professor in August 2020. In January 2022, PT was appointed as a Professor of Molecular Pathology and he currently serves as the head of the pathology unit at the Faculty of Medicine, University of Turku.
Professor Pekka Taimen has 20 years of experience in cell and molecular biology as well as in translational research. The main focus of his research group is on human diseases caused by lamin mutations, such as cardiomyopathies and premature aging syndrome. More recently, PT has also actively worked on prostate and bladder cancer related projects including novel biomarkers, biobanking, patient derived cell lines and improved imaging techniques utilizing digital pathology and machine learning approaches.
Pekka Taimen has more than 10 years of experience in teaching medical students at the Institute of Biomedicine, University of Turku. He has served first as a university teacher and from 2012 as a clinical lecturer. In 2015 PT received the Lecturer of the Year award in the Faculty of Medicine.
- Radiomics and machine learning of multisequence multiparametric prostate MRI: Towards improved non-invasive prostate cancer characterization (2019)
- PLoS ONE
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Repeatability of radiomics and machine learning for DWI: Short-term repeatability study of 112 patients with prostate cancer (2019)
- Magnetic Resonance in Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Reply to Mengxin Lu, Yi Zhang, Yu Xiao's Letter to the Editor, re: Kimmo Kettunen, Peter J. Bostrom, Tarja Lamminen, et al. Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells. Eur Urol 2019;76:430-4 (2019)
- European Urology
(O2 Muu julkaisu ) - SORLA regulates endosomal trafficking and oncogenic fitness of HER2 (2019)
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Urine cytology is a feasible tool for assessing erythematous bladder lesions after bacille Calmette-Guérin (BCG) treatment (2019)
- BJU International
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Validation of IMPROD biparametric MRI in men with clinically suspected prostate cancer: A prospective multi-institutional trial (2019)
- PLoS Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - ANO7 is associated with aggressive prostate cancer (2018)
- International Journal of Cancer
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - C-11-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial) (2018)
- Cancer Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer (2018)
- Endocrine-Related Cancer
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Laminopatiat - harvinaisten sairauksien kasvava joukko (2018)
- Duodecim
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - New prostate cancer grade grouping system predicts survival after radical prostatectomy (2018)
- Human Pathology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice (2018)
- BMC Research Notes
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial) (2018)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Radiomic features from pretreatment biparametric MRI predict prostate cancer biochemical recurrence: Preliminary findings (2018)
- Journal of Magnetic Resonance Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
- Prostate
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Fitting methods for intravoxel incoherent motion imaging of prostate cancer on region of interest level: Repeatability and gleason score prediction (2017)
- Magnetic Resonance in Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Immunological tumor status may predict response to neoadjuvant chemotherapy and outcome after radical cystectomy in bladder cancer (2017)
- Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Increased FGFRL1 expression is associated with prostate cancer progression (2017)
- Cancer Research
(O2 Muu julkaisu ) - Internal epithelia in Drosophila display rudimentary competence to form cytoplasmic networks of transgenic human vimentin (2017)
- FASEB Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Nestin contributes to skeletal muscle homeostasis and regeneration (2017)
- Journal of Cell Science
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )