Olli Pentikäinen
PhD
olli.pentikainen@utu.fi +358 40 521 6913 Kiinamyllynkatu 10 Turku ORCID identifier: https://orcid.org/0000-0001-7188-4016 |
Areas of expertise
Computer-Dependent Drug Discovery; Molecular Modeling; Protein structure-function relationship; Protein-protein interaction
Computer-Dependent Drug Discovery; Molecular Modeling; Protein structure-function relationship; Protein-protein interaction
Biography
Education:
MSc in (organic) chemistry 1995 (University of Joensuu, Finland)
PhD in Biochemistry 2003 (Åbo Akademi University)
Adjunct Professor in Biochemistry 2005- (University of Turku)
Positions:
2017- Professor of Medicinal Chemistry (University of Turku) 8/2017
2011- Senior Lecturer in Cell and Molecular Biology (University of Jyväskylä)
2015 Visiting Senior Scientist (University of Innsbruck, Austria)
2005-2006 Visiting Senior Scientist (University of Bristol, UK)
1999-2005 Manager in Molecular Discovery (FBD Ltd)
Education:
MSc in (organic) chemistry 1995 (University of Joensuu, Finland)
PhD in Biochemistry 2003 (Åbo Akademi University)
Adjunct Professor in Biochemistry 2005- (University of Turku)
Positions:
2017- Professor of Medicinal Chemistry (University of Turku) 8/2017
2011- Senior Lecturer in Cell and Molecular Biology (University of Jyväskylä)
2015 Visiting Senior Scientist (University of Innsbruck, Austria)
2005-2006 Visiting Senior Scientist (University of Bristol, UK)
1999-2005 Manager in Molecular Discovery (FBD Ltd)
Research
Our research focuses on discovery of efficient drug candidates and development of novel methods for that purpose. Especially our research on cancer drug targets that have been considered highly difficult, together with risk analysis of drug candidates, pave the road for safer drugs.
Our research focuses on discovery of efficient drug candidates and development of novel methods for that purpose. Especially our research on cancer drug targets that have been considered highly difficult, together with risk analysis of drug candidates, pave the road for safer drugs.
Publications 
1 of 14
- Designing fluorescent estrogen mimetic 7-hydroxycoumarin probe substrates for human sulfotransferase enzymesAtomistic simulations reveal impacts of missense mutations on the structure and function of SynGAP1 (2025)
- European Journal of Pharmaceutical SciencesBriefings in Bioinformatics
(A1 Refereed original research article in a scientific journal) - Enhancing the Predictive Power of Macrocyclic Drug Permeability by Knowledge Distillation from Analogous Pretraining DataBuilding shape-focused pharmacophore models for effective docking screening (2025)
- Journal of Medicinal Chemistry
(A1 Refereed original research article in a scientific journal) - Ligand-Enhanced Negative Images Optimized for Docking Rescoring (2024)
(A1 Refereed original research article in a scientific journal) - (2024)
- Journal of cheminformatics
(A1 Refereed original research article in a scientific journal) - Oxazolidinones: Are they only good for the discovery of antibiotics? A worm's eye view (2023)
- Journal of Molecular StructureJournal of Chemical Information and Modeling
(A2 Refereed review article in a scientific journal ) - Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt ModulatorsComputational Study on the Inhibitory Effect of Natural Compounds against the SARS-CoV-2 ProteinsRational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase2023
- MoleculesJournal of Enzyme Inhibition and Medicinal Chemistry
(A1 Refereed original research article in a scientific journal) - (2022)
- Bioinorganic Chemistry and Applications
- 2022
- International Journal of Molecular Sciences
(A1 Refereed original research article in a scientific journal) - Optimization of Cavity-Based Negative Images to Boost Docking Enrichment in Virtual Screening (2022)
(A1 Refereed original research article in a scientific journal) - (2022)
(A1 Refereed original research article in a scientific journal)
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