Markus Juonala
Professor
mataju@utu.fi +358 29 450 2754 +358 50 478 3572 ORCID identifier: https://orcid.org/0000-0001-9498-364X |
Internal medicine; endocrinology; cardiovascular risk
Cardiovascular epidemiology, Young Finns Study, i3c consortium
Professor Markus Juonala (MD,
PhD, University of Turku) is a specialist in internal medicine and
endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he
has been conducting research on longitudinal studies examining the importance
of childhood risk factors on later cardiovascular health. His PhD work was
based primarily on the Cardiovascular Risk in Young Finns Study (University of
Turku, April 2005). Since 2008, he has had a major involvement in the
development of the International Childhood Cardiovascular Cohort (i3C)
Consortium that combines the efforts of the main longitudinal studies
worldwide. In June 2014, he was appointed as Professor of Internal Medicine at
the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute
(MCRI).
His career
publications total is 270 (h-index 44) with published highlights including a
first-author paper in the New England Journal of Medicine, the first-ranked
general medicine journal, one paper in JAMA, the third-ranked general medicine
journal and 30 papers (11 as first/last author) published in either the number
one, two, or three ranked cardiovascular disease journals (17 in Circulation,
five in the Journal of the American College of Cardiology, eight in the
European Heart Journal).
Professor Juonala’s
principal research focus has been to provide novel information on the effects
of childhood risk factors on cardiovascular health in adulthood. Beginning from
the summer of 2008 he has led a research group within the Young Finns Study and
i3c consortium with special interest on cardiometabolic risk factors. The most
important findings of his research have provided information on childhood and
early adulthood risk factors for atherosclerosis, suggesting that childhood
risk factors, such as dyslipidaemia, elevated blood pressure and smoking,
predict early atherosclerosis and its progression independent of adult risk
factors levels. Concerning cardiometabolic risk factors, his group has been
able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood
is predictive of carotid atherosclerosis and its progression in adulthood.
However, at the time of obesity epidemic, the most important findings concern
the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes
in lifestyle associated with weight maintenance or reduction improve
cardiovascular health.
Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs
Special interest areas: Acute internal medicine, endocrinology, lipidology
- Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey - A Meta-Analysis of Three Independent Studies (2012)
- PLoS ONE
(A1 Refereed original research article in a scientific journal) - High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis (2012)
- European Heart Journal
(A1 Refereed original research article in a scientific journal) - Ideal Cardiovascular Health in Childhood and Cardiometabolic Outcomes in Adulthood The Cardiovascular Risk in Young Finns Study (2012)
- Circulation
(A1 Refereed original research article in a scientific journal) - Lapsuuden elintavat vaikuttavat valtimotaudin kehittymiseen (2012)
- Lääkärilehti
(A2 Refereed review article in a scientific journal ) - Neuropeptide Y polymorphism increases the risk for asthma in overweight subjects; protection from atherosclerosis in asthmatic subjects--the cardiovascular risk in young Finns study (2012)
- Neuropeptides
(A1 Refereed original research article in a scientific journal) - No Association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study (2012)
- BMC Medical Genetics
(A1 Refereed original research article in a scientific journal) - Parental Smoking in Childhood and Brachial Artery Flow-Mediated Dilatation in Young Adults The Cardiovascular Risk in Young Finns Study and the Childhood Determinants of Adult Health Study (2012)
- Arteriosclerosis, Thrombosis, and Vascular Biology
(A1 Refereed original research article in a scientific journal) - Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study (2012)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Pregnancy complications and ultrasound measures of cardiovascular risk (2012)
- American Journal of Epidemiology
(Other publication) - Relation of high cytomegalovirus antibody titres to blood pressure and brachial artery flow-mediated dilation in young men: the Cardiovascular Risk in Young Finns Study (2012)
- Clinical and Experimental Immunology
(A1 Refereed original research article in a scientific journal) - Relation of total and free testosterone and sex hormone-binding globulin with cardiovascular risk factors in men aged 24-45 years. The Cardiovascular Risk in Young Finns Study (2012)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Socioeconomic Status, Cardiovascular Risk Factors, and Subclinical Atherosclerosis in Young Adults The Cardiovascular Risk in Young Finns Study (2012)
- Arteriosclerosis, Thrombosis, and Vascular Biology
(A1 Refereed original research article in a scientific journal) - Soluble Vascular Adhesion Protein-1 Correlates With Cardiovascular Risk Factors and Early Atherosclerotic Manifestations (2012)
- Arteriosclerosis, Thrombosis, and Vascular Biology
(A1 Refereed original research article in a scientific journal) - The role of pharmacotherapy in the prevention and treatment of paediatric metabolic syndrome - Implications for long-term health (2012)
- Pharmacological Research
(A1 Refereed original research article in a scientific journal) - Tissue inhibitor of matrix metalloproteinases 4 (TIMP4) in a population of young adults: Relations to cardiovascular risk markers and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study (2012)
- Scandinavian Journal of Clinical and Laboratory Investigation
(A1 Refereed original research article in a scientific journal) - When and how to start prevention of atherosclerosis? Lessons from the Cardiovascular Risk in the Young Finns Study and the Special Turku Coronary Risk Factor Intervention Project (2012)
- Pediatric Nephrology
(A2 Refereed review article in a scientific journal ) - Adulthood EAS-temperament and carotid artery intima-media thickness: The Cardiovascular Risk in Young Finns study (2011)
- Psychology and Health
(A1 Refereed original research article in a scientific journal) - A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study (2011)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Apolipoprotein B is related to arterial pulse wave velocity in young adults: the Cardiovascular Risk in Young Finns Study (2011)
- Atherosclerosis
(A1 Refereed original research article in a scientific journal) - Change in job strain and progression of atherosclerosis: The Cardiovascular Risk in Young Finns study (2011)
- Journal of Occupational Health Psychology
(A1 Refereed original research article in a scientific journal)