A1 Refereed original research article in a scientific journal

Neuropeptide Y polymorphism increases the risk for asthma in overweight subjects; protection from atherosclerosis in asthmatic subjects--the cardiovascular risk in young Finns study



Authors: Jaakkola U, Kakko T, Juonala M, Lehtimäki T, Viikari J, Jääskeläinen AE, Mononen N, Kähönen M, Koskinen T, Keltikangas-Järvinen L, Raitakari O, Kallio J

Publisher: CHURCHILL LIVINGSTONE

Publication year: 2012

Journal: Neuropeptides

Journal name in source: NEUROPEPTIDES

Journal acronym: NEUROPEPTIDES

Number in series: 6

Volume: 46

Issue: 6

First page : 321

Last page: 328

Number of pages: 8

ISSN: 0143-4179

DOI: https://doi.org/10.1016/j.npep.2012.09.005


Abstract
Conclusions: Overweight together with the NPY-399T allele without NPY-Pro7 allele was associated with increased risk for asthma. Atherosclerosis was decreased in subjects with asthma depending on the NPY genotype. The results reveal novel insights into the genetics and biology of the relationship of atherosclerosis and asthma. (C) 2012 Elsevier All rights reserved.



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