A1 Refereed original research article in a scientific journal

Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey - A Meta-Analysis of Three Independent Studies




AuthorsHernesniemi JA, Seppala I, Lyytikainen LP, Mononen N, Oksala N, Hutri-Kahonen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kahonen M, Raitakari OT, Lehtimaki T

PublisherPUBLIC LIBRARY SCIENCE

Publication year2012

JournalPLoS ONE

Journal name in sourcePLOS ONE

Journal acronymPLOS ONE

Article numberARTN e28931

Number in series1

Volume7

Issue1

Number of pages10

ISSN1932-6203

DOIhttps://doi.org/10.1371/journal.pone.0028931


Abstract
Conclusion: Genetic profiling, by using known CAD risk variants, should not improve risk stratification for subclinical atherosclerosis beyond conventional risk factors among healthy young adults.



Last updated on 2024-26-11 at 21:36