Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 |
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
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- Solution phase synthesis of short oligoribonucleotides on a precipitative tetrapodal support (2014)
- Beilstein Journal of Organic Chemistry
- Synthesis of multi-galactose-conjugated 2´-O-methyl oligoribonucleotides and their in vivo imaging with positron emission tomography (2014)
- Bioorganic and Medicinal Chemistry
- Solution-Phase Synthesis of Short Oligo-2'-deoxyribonucleotides by Using Clustered Nucleosides as a Soluble Support (2013)
- European Journal of Organic Chemistry
- Synthesis of Fluorine-Labeled Peptide Nucleic Acid Building Blocks as Sensors for the 19F NMR Spectroscopic Detection of Different Hybridization Modes (2013)
- Journal of Organic Chemistry
- Synthesis of Short Oligodeoxyribonucleotides by Phosphotriester Chemistry on a Precipitative Tetrapodal Support (2013)
- European Journal of Organic Chemistry
- Synthesis of short oligodeoxyribonucleotides by phosphotriester chemistry on a precitative tetrapodal support (2013)
- European Journal of Organic Chemistry
- Zn2+ Complexes of 3,5-Bis[(1,5,9-triazacyclododecan-3-yloxy)methyl]phenyl Conjugates of Oligonucleotides as Artificial RNases: The Effect of Oligonucleotide Conjugation on Uridine Selectivity of the Cleaving Agent (2013)
- Helvetica Chimica Acta
- Acetylated and Methylated beta-Cyclodextrins as Viable Soluble Supports for the Synthesis of Short 2 '-Oligodeoxyribo-nucleotides in Solution (2012)
- Molecules
- Preclinical biodistribution studies of Ga-68-labeled anti-miR15b molecules (2012)
- BONE
- Solid-Supported NOTA and DOTA Chelators Useful for the Synthesis of 3 '-Radiometalated Oligonucleotides (2012)
- Bioconjugate Chemistry
- Syntheis of Biotinylated Multipodal Glycoclusters on a Solid Support (2012)
- European Journal of Organic Chemistry
- Synthesis of Biotinylated Multipodal Glycoclusters on a Solid Support (2012)
- European Journal of Organic Chemistry
- Click conjugation of 4´-C-modified oligonucleotides (2011) Anu Kiviniemi, Pasi Virta, Harri Lönnberg
- Effect of a Uracil Specific Binding for the Nuclease Activity of Bis(azacrown)conjugated 2´-O-Methyl Oligoribonucleotides (2011) Teija Niittymäki, Ekaterina Burakova, Anna Leisvuori, Pasi Virta, Harri Lönnberg
- Invasion of 2´-O-methyl oligoribonucleotides and their aminoglycoside conjugates to a 19F labelled HIV-1 TAR model (2011) Anu Kiviniemi, Pasi Virta
- Single-label time-resolved luminescence assay for estrogen receptor-ligand binding (2011)
- Analytical Biochemistry
- Solid-Supported 2 '-O-Glycoconjugation of Oligonucleotides by Azidation and Click Reactions (2011)
- Bioconjugate Chemistry
- Synthesis of Aminoglycoside-3 '-Conjugates of 2 '-O-Methyl Oligoribonucleotides and Their Invasion to a F-19 labeled HIV-1 TAR Model (2011)
- Bioconjugate Chemistry
- THE Zn2+ COMPLEX OF 1,4,7,10-TETRAAZACYCLODODECANE AS AN ARTIFICIAL NUCLEOBASE (2011)
- Nucleosides, Nucleotides and Nucleic Acids
- Characterization of RNA Invasion by F-19 NMR Spectroscopy (2010)
- Journal of the American Chemical Society
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