Professor Pasi Virta - UTU Research Portal

Pasi Virta
Professor

- Professor,
Pharmaseutical Chemistry (Department of Chemistry)

pamavi@utu.fi

+358 29 450 3209

+358 50 328 5719

: https://orcid.org/https://orcid.org/0000-0002-6218-2212

Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation

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Probing the nucleobase selectivity of RNA polymerases with dual-coding substrates (2024)
- Journal of Biological Chemistry
Mäkinen, Janne J.; Rosenqvist, Petja; Virta, Pasi; Metsä-Ketelä, Mikko; Belogurov, Georgiy A.
Tuning the Solubility of Soluble Support Constructs in Liquid Phase Oligonucleotide Synthesis (2024)
- Journal of Organic Chemistry
Rosenqvist, Petja; Saari, Verneri; Ora, Mikko; Molina, Alejandro Gimenez; Horvath, Andras; Virta, Pasi
5'-O-(2-Isopropoxyprop-2-yl)-protected Phosphoramidite Building Blocks in the Liquid Phase Oligonucleotide Synthesis (2023)
- European Journal of Organic Chemistry
Liang Zehong, Rosenqvist Petja, Pajuniemi Ella, Ora Mikko, Heinonen Petri, Virta Pasi, Oivanen Mikko
Assembly of split aptamers by dynamic pH-responsive covalent ligation (2023)
- Chemical Communications
Aho Aapo, Virta Pasi
In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography (2023)
- Molecular Pharmaceutics
Äärelä Antti, Auchynnikava Tatsiana, Moisio Olli, Liljenbäck Heidi, Andriana Putri, Iqbal Imran, Lehtimäki Jyrki, Rajander Johan, Salo Harri, Roivainen Anne, Airaksinen Anu J., Virta Pasi
Pretargeted PET imaging of trans-cyclooctene functionalized spherical nucleic acids (2023)
- Nuclear Medicine and Biology
Auchynnikava Tatsiana, Äärelä Antti, Liljenbäck Heidi, Andriana Putri, Kovacs Luciana, Li Xiang-Guo, Virta Pasi, Roivainen Anne, Airaksinen Anu
Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway (2023)
- ACS Chemical Biology
Artukka Erika, Schnell Robert, Palmu Kaisa, Rosenqvist Petja, Szodorai Edit, Niemi Jarmo, Virta Pasi, Schneider Gunter, Metsä-Ketelä Mikko
Stereo-Controlled Liquid Phase Synthesis of Phosphorothioate Oligonucleotides on a Soluble Support (2023)
- Journal of Organic Chemistry
Rosenqvist Petja, Saari Verneri, Pajuniemi Ella, Molina Alejandro Gimenez, Ora Mikko, Horvath Andras, Virta Pasi
Synthesis of Site-Specific Antibody-[60]Fullerene-Oligonucleotide Conjugates for Cellular Targeting (2023)
- ACS Applied Bio Materials
Äärelä Antti, Räsänen Kati, Holm Patrik, Salo Harri, Virta Pasi
Tetrazine Glycoconjugate for Pretargeted Positron Emission Tomography Imaging of trans-Cyclooctene-Functionalized Molecular Spherical Nucleic Acids (2023)
- ACS Omega
Auchynnikava Tatsiana, Äärelä Antti, Liljenbäck Heidi, Järvinen Juulia, Andriana Putri, Kovacs Luciana, Rautio Jarkko, Rajander Johan, Virta Pasi, Roivainen Anne, Li Xiang-Guo, Airaksinen Anu J.