Pasi Virta
Professor
pamavi@utu.fi +358 29 450 3209 +358 50 328 5719 ORCID identifier: https://orcid.org/https://orcid.org/0000-0002-6218-2212 |
Areas of expertise
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Synthesis of oligonucleotide, peptide nucleic acid, peptide (including antibodies) and carbohydrate conjugates, Drug delivery strategies of oligonucleotides, mechanistic studies of higher order secondary structures of nucleic acids, 19F NMR spectroscopy, DNA-templated synthesis, aqueous glycosylation
Publications
- Covalently Mercurated Molecular Beacon for Discriminating the Canonical Nucleobases (2021)
- ChemBioChemOrganic Letters
(A1 Refereed original research article in a scientific journal) - Drug-to-Antibody Ratio Estimation via Proteoform Peak Integration in the Analysis of Antibody-Oligonucleotide Conjugates with Orbitrap Fourier Transform Mass Spectrometry (2021)
- Analytical ChemistryCurrent Protocols in Nucleic Acid Chemistry
(A1 Refereed original research article in a scientific journal) - Expanding the Scope of the Cleavable N-(Methoxy)oxazolidine Linker for the Synthesis of Oligonucleotide Conjugates (2021)
- MoleculesACS Omega
(A1 Refereed original research article in a scientific journal) - More versatile synthesis of oligonucleotides (2021)
- Science
(B1 Non-refereed article in a scientific journal) - Stability of the Phosphotriester PDE6D Inhibitors (2021)
- ChemistrySelect
(A1 Refereed original research article in a scientific journal) - Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support (2021)
- RSC Advances
(A1 Refereed original research article in a scientific journal) - The mechanism of the nucleo-sugar selection by multi-subunit RNA polymerases (2021)
- Nature Communications
(A1 Refereed original research article in a scientific journal) - Conjugation of Oligonucleotides to Peptide Aldehydes via a pH-Responsive N-Methoxyoxazolidine Linker (2020)
(A1 Refereed original research article in a scientific journal) - Immobilized Carbohydrates for Preparation of 3'-Glycoconjugated Oligonucleotides (2020)
(A1 Refereed original research article in a scientific journal) - PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity (2020)
(A1 Refereed original research article in a scientific journal)



