Alex Dickens - UTU Research Portal

Alex Dickens

- Academy Research Fellow,
Turku Bioscience Centre (Independent units)
- Docent,
Department of Life Technologies (Faculty of Technology)
- Academy Research Fellow,
Analytiikkakeskus (Department of Chemistry)

alex.dickens@utu.fi

: https://orcid.org/0000-0002-3178-8449(external)

Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

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Lihomisriski on yhteydessä aivojen insuliini- ja reseptorimuutoksiin (2021)
- Duodecim
Kantonen T., Pekkarinen L., Karjalainen T., Bucci M., Kalliokoski K., Haaparanta-Solin M., Aarnio R., Dickens A.M., von Eyken A., Laitinen K., Houttu N., Kirjavainen A.K., Helin S., Hirvonen J., Rönnemaa T., Nuutila P., Nummenmaa L.
Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways (2021)
- Cell Reports
Partho Sen, Syed Bilal Ahmad Andrabi, Tanja Buchacher, Mohd Moin Khan, Ubaid Ullah Kalim, Tuomas Mikael Lindeman, Marina Amaral Alves, Victoria Hinkkanen, Esko Kemppainen, Alex M Dickens, Omid Rasool, Tuulia Hyötyläinen, Riitta Lahesmaa, Matej Orešič
Systems biology approaches to study lipidomes in health and disease (2021)
- Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
Marina Amaral Alves, Santosh Lamichhane, Alex Dickens, Aidan McGlinchey, Henrique C Ribeiro, Partho Sen, Fang Wei, Tuulia Hyötyläinen, Matej Orešič
Integrative Analysis of Circulating Metabolite Profiles and Magnetic Resonance Imaging Metrics in Patients with Traumatic Brain Injury (2020)
- International Journal of Molecular Sciences
Ilias Thomas, Alex M. Dickens, Jussi P. Posti, Mehrbod Mohammadian, Christian Ledig, Riikka S. K. Takala, Tuulia Hyötyläinen, Olli Tenovuo, Matej Orešič
Links between central CB1-receptor availability and peripheral endocannabinoids in patients with first episode psychosis (2020)
- NPJ Schizophrenia
Dickens Alex M, Borgan Faith, Laurikainen Heikki, Lamichhane Santosh, Marques Tiago, Rönkkö Tuukka, Veronese Mattia, Lindeman Tuomas, Hyötyläinen Tuulia, Howes Oliver, Hietala Jarmo, Orešič Matej
Metabolic alterations in immune cells associate with progression to type 1 diabetes (2020)
- Diabetologia
Partho Sen, Alex M. Dickens, María Asunción López-Bascón, Tuomas Lindeman, Esko Kemppainen, Santosh Lamichhane, Tuukka Rönkkö, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Heikki Hyöty, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes (2020)
- Environment International
Aidan McGlinchey, Tim Sinioja, Santosh Lamichhane, Partho Sen, Johanna Bodin, Heli Siljander, Alex M Dickens, Dawei Geng, Cecilia Carlsson, Daniel Duberg, Jorma Ilonen, Suvi M Virtanen, Hubert Dirven, Hanne F Bentsen, Karin Zimmer, Unni C Nygaard, Matej Oresic, Mikael Knip, Tuulia Hyotylainen
Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation (2019)
- EJNMMI Research
Vainio SK, Dickens AM, Tuisku J, Eskola O, Solin O, Loyttyniemi E, Anthony DC, Rinne JO, Airas L, Haaparanta-Solin M
Cord-Blood Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes (2019)
- Biomolecules
Lamichhane Santosh, Ahonen Linda, Dyrlund Thomas Spartholt, Dickens Alex M., Siljander Heli, Hyöty Heikki, Ilonen Jorma, Toppari Jorma, Veijola Riitta, Hyötyläinen Tuulia, Knip Mikael, Oresic Matej
Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury (2019)
- Journal of Neurotrauma
Posti JP, Takala RS, Lagerstedt L, Dickens AM, Hossain I, Mohammadian M, Ala-Seppälä HM, Frantzén J, Van Gils M, Hutchinson PJ, Katila AJ, Maanpää HR, Menon D, Newcombe V, Tallus J, Hrusovsky K, Wilson D, Gill J, Sanchez JC, Tenovuo O, Zetterberg H, Blennow K.
Impaired insulin sensitivity is associated with worsening cognition in HIV-infected patients (2019)
- Neurology
Khuder SS, Chen SM, Letendre S, Marcotte T, Grant I, Franklin D, Rubin LH, Margolick JB, Jacobson LP, Sacktor N, D'Souza G, Stosor V, Lake JE, Rapocciolo G, McArthur JC, Dickens AM, Haughey NJ, Haughey NJ
Lipidomic characterization of extracellular vesicles in human serum (2019)
- Journal of Circulating Biomarkers
Chen S., Datta-Chaudhuri A., Deme P., Dickens A., Dastgheyb R., Bhargava P., Bi H., Haughey N.J.
Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry (2019)
- Analytical and Bioanalytical Chemistry
Samira Salihović, Alex M. Dickens, Ida Schoultz, Frida Fart, Lisanna Sinisalu, Tuomas Lindeman, Jonas Halfvarson, Matej Orešič, Tuulia Hyötyläinen
The Role of Omic Technologies in the Study of the Human Gut Microbiome (2019) Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
An Overview of Metabolomics Data Analysis: Current Tools and Future Perspectives (2018) Comprehensive Analytical Chemistry Lamichhane S., Sen P., Dickens A., Hyötyläinen T., Orešič M.
Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe (2018)
- Methods
Santosh Lamichhane, Partho Sen, Alex M.Dickens, Matej Orešič, Hanne Christine Bertram
Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury (2018)
- Journal of Neurotrauma
Dickens AM, Posti JP, Takala RSK, Ala-Seppala H, Mattila I, Coles JP, Frantzen J, Hutchinson PJ, Katila AJ, Kyllonen A, Maanpaa HR, Newcombe V, Outtrim J, Tallus J, Carpenter KLH, Menon DK, Hyotylainen T, Tenovuo O, Oresic M, Oresic M
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions (2017)
- Science Signaling
Dickens AM, Tovar-y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ
Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging (2017)
- Scientific Reports
Dickens AM, Yoo SW, Chin AC, Xu JD, Johnson TP, Trout AL, Hauser KF, Haughey NJ
HIV Tat protein and amyloid-beta peptide form multifibrillar structures that cause neurotoxicity (2017)
- Nature Structural and Molecular Biology
Hategan A, Bianchet MA, Steiner J, Karnaukhova E, Masliah E, Fields A, Lee MH, Dickens AM, Haughey N, Dimitriadis EK, Nath A