Alex Dickens
 


alex.dickens@utu.fi




ORCID identifier: https://orcid.org/0000-0002-3178-8449

Areas of expertise
Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

Publications
  
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  • Metabolic effects and biotransformation of perfluorohexyloctane in human hepatocytes  (2026)  
    • Environment International
     Alijagic, Andi; Chaker, Jade; Barbosa, João Marcos G.; Duberg, Daniel; Castro-Alves, Victor; Dickens, Alex M.; Orešič, Matej; Hyötyläinen, Tuulia
    (    A1 Refereed original research article in a scientific journal)


  • Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity  (2026)  
    • Nature CommunicationsJHEP Reports
     Lamichhane, Santosh; Dickens, Alex M.; Buchacher, Tanja; Lou, Tianai; Charron-Lamoureux, Vincent; Kattelus, Roosa; Karmacharya, Pragya; Pinto da Silva, Lucas; Kråkström, Matilda; Rasool, Omid; Sen, Partho; Walker, Corinn; Patan, Abubaker; Gentry, Emily C.; Zuffa, Simone; Arzoomand, Aron; Lakshmikanth, Tadepally; Mikeš, Jaromir; Mebrahtu, Aman; Vatanen, Tommi; Raffatellu, Manuela; Zengler, Karsten; Hyötyläinen, Tuulia; Xavier, Ramnik J.; Brodin, Petter; Lahesmaa, Riitta; Dorrestein, Pieter C.; Knip, Mikael; Orešič, Matej
    (    A1 Refereed original research article in a scientific journal)


  • Pre- and postnatal maternal psychological distress and the metabolomic profile of human milkCholesterol Ester Storage Disease in Two Field Spaniels With Lysosomal Acid Lipase Deficiency  (2026
    • Journal of Nutrition
     Ryan, Niamh; Sundekilde, Ulrik Kramer; Dickens, Alex M.; Kalant, Henna-Maria; Leahy-Warren, Patricia; Philpott, Lloyd; Mulcahy, Helen; Lamichhane, Santosh; Isokääntä, Heidi; Perasto, Laura; Tarro, Saija; Karlsson, Hasse; Karlsson, Linnea; O’Mahony, Siobhain M.; Aatsinki, Anna-KatariinaA1 Refereed original research article in a scientific journal


  • Progressive fibrosis in human MASLD is associated with spatially linked transcriptomic signatures of metabolic reprogramming and senescenceDoes cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial  (2026)  
       Vu, Hani; Sun, Yuliangzi; Xiong, Zherui; Tan, Xiao; Radford-Smith, Daniel; Causer, Andrew; Dickens, Alex M.; Hyötyläinen, Tuulia; Evstafev, Ilia; Oresic, Matej; Nefzger, Christian; O’Sullivan, Eoin D.; Watt, Matthew J.; Ramm, Grant A.; Clouston, Andrew; Irvine, Katharine M.; Nguyen, Quan H.; Powell, Elizabeth E.
      (      A1 Refereed original research article in a scientific journal)


    •   (2025)  
      • Journal of Veterinary Internal MedicineiScience
       Syrjä, Pernilla; Ylenius, Mathilda M. H.; Kråkström, Matilda; Dickens, Alex M.; Rautala, Elina; Huupponen, Anna; Eriksson, Anders; Viitanen, Sanna J.
      (      A1 Refereed original research article in a scientific journal)


    •   (2025)  
      • Neuropsychopharmacology
       Chesney, Edward; Oliver, Dominic; Sarma, Ananya; Lamper, Ayse Doga; Slimani, Ikram; Lloyd, Millie; Dickens, Alex M.; Welds, Michael; Kråkström, Matilda; Gasparini-Andre, Irma; Oresic, Matej; Lawn, Will; Babayeva, Natavan; Freeman, Tom P.; Englund, Amir; Strang, John; McGuire, Philip
      (      A1 Refereed original research article in a scientific journal)


    • Dynamics of gut metabolome and microbiota maturation during early life  (2025)  
         Aatsinki, Anna-Katariina; Lamichhane, Santosh; Isokääntä, Heidi; Sen, Partho; Kråkström, Matilda; Amaral Alves, Marina; Keskitalo, Anniina; Munukka, Eveliina; Karlsson, Hasse; Perasto, Laura; Lukkarinen, Minna; Oresic, Matej; Kailanto, Henna-Maria; Karlsson, Linnea; Lahti, Leo; Dickens, Alex M.
        (        A1 Refereed original research article in a scientific journal)


      • Intra- and inter-individual variation of the human lipidomePrenatal exposure to perfluoroalkyl substances predicts multimodal brain structural and functional outcomes in children aged 5 years: a birth cohort study  (2025)  
        • Trends in Analytical Chemistry
         Anh, Nguyen Hoang; Beyene, Habtamu B.; Mocciaro, Gabriele; Hahnefeld, Lisa; Lamichhane, Santosh; Fabritius, Mikael; Avela, Henri; Wang, Yuqin; Dickens, Alex M.; Gurke, Robert; Yang, Baoru; Griffiths, William J.; Hyötyläinen, Tuulia; Meikle, Peter J.; Orešič, Matej
        (        A2 Refereed review article in a scientific journal )


      • Perfluorooctanoic acid disrupts hepatic metabolism in the developing chicken embryo  (2025)  
        • MetabolomicsAnalytical Chemistry
         Scherbak, Nikolai; Duberg, Daniel; Kråkström, Matilda; Tikka, Pauli; Dickens, Alex M.; Engwall, Magnus; Orešič, Matej; Hyötyläinen, Tuulia
        (        A1 Refereed original research article in a scientific journal)


      •   (2025)  
        • The Lancet Planetary HealthAnalytical Chemistry
         Barron, Aaron; Dickens, Alex M; Tuulari, Jetro J; Hyötylainen, Tuulia; Kortesluoma, Susanna; Merisaari, Harri; Pulli, Elmo P; Silver, Eero; Kumpulainen, Venla; Copeland, Anni; Saukko, Ekaterina; Lewis, John D; Karlsson, Linnea; Orešič, Matej; Karlsson, Hasse
        (        A1 Refereed original research article in a scientific journal)


      • The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research  (2025)  
           Nguyen, Anh Hoang; Castro-Alves, Victor; Holmström, Flores Emilia; Barbosa, João Marcos G.; Kråkström, Matilda; Reinivuori, Päivikki; Kauko, Otto; Dickens, Alex; Orešič, Matej; Hyötyläinen, Tuulia
          (          A1 Refereed original research article in a scientific journal)


        • Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization  (2024)  
             Isokääntä, Heidi; Pinto da Silva, Lucas; Karu, Naama; Kallonen, Teemu; Aatsinki, Anna-Katariina; Hankemeier, Thomas; Schimmel, Leyla; Diaz, Edgar; Hyötyläinen, Tuulia; Dorrestein, Pieter C.; Knight, Rob; Orešič, Matej; Kaddurah-Daouk, Rima; Dickens, Alex M.; Lamichhane, SantoshA1 Refereed original research article in a scientific journal


          • Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards  (2024)  
            • Nature Communications
             Torta F., Hoffmann N., Burla B., Alecu I., Arita M., Bamba T., Bennett S.A.L., Bertrand-Michel J., Brügger B., Cala M.P., Camacho-Muñoz D., Checa A., Chen M., Chocholoušková M., Cinel M., Chu-Van E., Colsch B., Coman C., Connell L., Sousa B.C., Dickens A.M., Fedorova M., Eiríksson F.F., Gallart-Ayala H., Ghorasaini M., Giera M., Guan X.L., Haid M., Hankemeier T., Harms A., Höring M., Holčapek M., Hornemann T., Hu C., Hülsmeier A.J., Huynh K., Jones C.M., Ivanisevic J., Izumi Y., Köfeler H.C., Lam S.M., Lange M., Lee J.C., Liebisch G., Lippa K., Lopez-Clavijo A.F., Manzi M., Martinefski M.R., Math R.G.H., Mayor S., Meikle P.J., Monge M.E., Moon M.H., Muralidharan S., Nicolaou A., Nguyen-Tran T., O'Donnell V.B., Orešič M., Ramanathan A., Riols F., Saigusa D., Schock T.B., Schwartz-Zimmermann H., Shui G., Singh M., Takahashi M., Thorsteinsdóttir M., Tomiyasu N., Tournadre A., Tsugawa H., Tyrrell V.J., van der Gugten G., Wakelam M.O., Wheelock C.E., Wolrab D., Xu G., Xu T., Bowden J.A., Ekroos K., Ahrends R., Wen
            (            A1 Refereed original research article in a scientific journal)


          • Infant gut microbiota and negative and fear reactivityMultiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors  (2024)  
            • Development and Psychopathology
             Huovinen, Venla; Aatsinki, Anna-Katariina; Kataja, Eeva-Leena; Munukka, Eveliina; Keskitalo, Anniina; Lamichhane, Santosh; Raunioniemi, Peppi; Bridgett, David J.; Lahti, Leo; O’Mahony, Siobhain M.; Dickens, Alex; Korja, Riikka; Karlsson, Hasse; Nolvi, Saara; Karlsson, Linnea
            (            A1 Refereed original research article in a scientific journal)


          •   (2024)  
            • Metabolomics
             Cruz, Abraham Kuri; Alves, Marina Amaral; Andresson, Thorkell; Bayless, Amanda L.; Bloodsworth, Kent J.; Bowden, John A.; Bullock, Kevin; Burnet, Meagan C.; Carnevale Neto, Fausto; Choy, Angelina; Clish, Clary B.; Couvillion, Sneha P.; Cumeras, Raquel; Dailey, Lucas; Dallmann, Guido; Davis, W. Clay; Deik, Amy A.; Dickens, Alex M.; Djukovic, Danijel; Dorrestein, Pieter C.; Eder, Josie G.; Fiehn, Oliver; Flores, Roberto; Gika, Helen; Hagiwara, Kehau A.; Pham, Tuan Hai; Harynuk, James J.; Aristizabal-Henao, Juan J.; Hoyt, David W.; Jean-Francois, Focant; Krakstroem, Matilda; Kumar, Amit; Kyle, Jennifer E.; Lamichhane, Santosh; Li, Yuan; Nam, Seo Lin; Mandal, Rupasri; de la Mata, A. Paulina; Meehan, Michael J.; Meikopoulos, Thomas; Metz, Thomas O.; Mouskeftara, Thomai; Munoz, Nathalie; Gowda, G. A. Nagana; Orešic, Matej; Panitchpakdi, Morgan; Pierre-Hugues, Stefanuto; Raftery, Daniel; Rushing, Blake; Schock, Tracey; Seifried, Harold; Servetas, Stephanie; Shen, Tong; Sumner, Susan; Carrillo, Kieran S. Tarazona; Thibaut, Dejong; Trejo, Jesse B.; Van Meulebroek, Lieven; Vanhaecke, Lynn; Virgiliou, Christina; Weldon, Kelly C.; Wishart, David S.; Zhang, Lu; Zheng, Jiamin; Da Silva, Sandra
            (            A1 Refereed original research article in a scientific journal)


          • Novel Lipid Formulation Increases Absorption of Oral Cannabidiol (CBD)  (2024)  
            • Pharmaceutics
             Chesney, Edward; Mazibuko, Ndabezinhle; Oliver, Dominic; Minichino, Amedeo; Lamper, Ayse Doga; Chester, Lucy; Reilly, Thomas J.; Lloyd, Millie; Krakstrom, Matilda; Dickens, Alex M.; Oresic, Matej; Lynch, Eric; Stoloff, Gregory; Mehta, Mitul A.; Mcguire, Philip
            (            A1 Refereed original research article in a scientific journal)


          • Serum lipidome associates with neuroimaging features in patients with traumatic brain injury2024
            • iScience
             Thomas, Ilias; Newcombe, Virginia F.J.; Dickens, Alex M.; Richter, Sophie; Posti, Jussi P.; Maas, Andrew I.R.; Tenovuo, Olli; Hyötyläinen, Tuulia; Büki, András; Menon, David K.; Orešič, Matej
            (            A1 Refereed original research article in a scientific journal)


          • Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic dietCirculating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children  (2023)  
            • Frontiers in Molecular BiosciencesFrontiers in Endocrinology
             Dickens Alex M, Johnson Tory P, Lamichhane Santosh, Kumar Anupama, Pardo Carlos A, Gutierrez Erie G, Haughey Norman, Cervenka Mackenzie C
            (            A1 Refereed original research article in a scientific journal)


          •   (2023)  
               Lamichhane Santosh, Sen Partho, Dickens Alex M, Kråkström Matilda, Ilonen Jorma, Lempainen Johanna, Hyöty Heikki, Lahesmaa Riitta, Veijola Riitta, Toppari Jorma, Hyötyläinen Tuulia, Knip Mikael, Orešič Matej

              (              A1 Refereed original research article in a scientific journal)


            • Dynamics of the Lipidome in a Colon Simulator  (2023)  
              • Metabolites
               Kråkström Matilda, Dickens Alex M, Amaral Alves Marina, Forssten Sofia D, Ouwehand Arthur C, Hyötyläinen Tuulia, Orešič Matej, Lamichhane Santosh
              (              A1 Refereed original research article in a scientific journal)



            Last updated on 12/07/2023 11:40:00 AM