Alex Dickens
 


alex.dickens@utu.fi




ORCID identifier: https://orcid.org/0000-0002-3178-8449

Areas of expertise
Analytical chemistry; metabolomics; lipidomics; bioinformatics; systems medicine

Publications
  
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  • Metabolic effects and biotransformation of perfluorohexyloctane in human hepatocytes  (2026)  
    • Environment International
     Alijagic, Andi; Chaker, Jade; Barbosa, João Marcos G.; Duberg, Daniel; Castro-Alves, Victor; Dickens, Alex M.; Orešič, Matej; Hyötyläinen, Tuulia
    (    A1 Refereed original research article in a scientific journal)


  • Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity  (2026)  
    • Nature Communications
     Lamichhane, Santosh; Dickens, Alex M.; Buchacher, Tanja; Lou, Tianai; Charron-Lamoureux, Vincent; Kattelus, Roosa; Karmacharya, Pragya; Pinto da Silva, Lucas; Kråkström, Matilda; Rasool, Omid; Sen, Partho; Walker, Corinn; Patan, Abubaker; Gentry, Emily C.; Zuffa, Simone; Arzoomand, Aron; Lakshmikanth, Tadepally; Mikeš, Jaromir; Mebrahtu, Aman; Vatanen, Tommi; Raffatellu, Manuela; Zengler, Karsten; Hyötyläinen, Tuulia; Xavier, Ramnik J.; Brodin, Petter; Lahesmaa, Riitta; Dorrestein, Pieter C.; Knip, Mikael; Orešič, Matej
    (    A1 Refereed original research article in a scientific journal)


  • Progressive fibrosis in human MASLD is associated with spatially linked transcriptomic signatures of metabolic reprogramming and senescence  (2026)  
    • JHEP Reports
     Vu, Hani; Sun, Yuliangzi; Xiong, Zherui; Tan, Xiao; Radford-Smith, Daniel; Causer, Andrew; Dickens, Alex M.; Hyötyläinen, Tuulia; Evstafev, Ilia; Oresic, Matej; Nefzger, Christian; O’Sullivan, Eoin D.; Watt, Matthew J.; Ramm, Grant A.; Clouston, Andrew; Irvine, Katharine M.; Nguyen, Quan H.; Powell, Elizabeth E.
    (    A1 Refereed original research article in a scientific journal)


  • Cholesterol Ester Storage Disease in Two Field Spaniels With Lysosomal Acid Lipase Deficiency  (2025)  
    • Journal of Veterinary Internal Medicine
     Syrjä, Pernilla; Ylenius, Mathilda M. H.; Kråkström, Matilda; Dickens, Alex M.; Rautala, Elina; Huupponen, Anna; Eriksson, Anders; Viitanen, Sanna J.
    (    A1 Refereed original research article in a scientific journal)


  • Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial  (2025)  
    • Neuropsychopharmacology
     Chesney, Edward; Oliver, Dominic; Sarma, Ananya; Lamper, Ayse Doga; Slimani, Ikram; Lloyd, Millie; Dickens, Alex M.; Welds, Michael; Kråkström, Matilda; Gasparini-Andre, Irma; Oresic, Matej; Lawn, Will; Babayeva, Natavan; Freeman, Tom P.; Englund, Amir; Strang, John; McGuire, Philip
    (    A1 Refereed original research article in a scientific journal)


  • Dynamics of gut metabolome and microbiota maturation during early life  (2025)  
    • iScience
     Aatsinki, Anna-Katariina; Lamichhane, Santosh; Isokääntä, Heidi; Sen, Partho; Kråkström, Matilda; Amaral Alves, Marina; Keskitalo, Anniina; Munukka, Eveliina; Karlsson, Hasse; Perasto, Laura; Lukkarinen, Minna; Oresic, Matej; Kailanto, Henna-Maria; Karlsson, Linnea; Lahti, Leo; Dickens, Alex M.
    (    A1 Refereed original research article in a scientific journal)


  • Intra- and inter-individual variation of the human lipidome  (2025)  
    • Trends in Analytical Chemistry
     Anh, Nguyen Hoang; Beyene, Habtamu B.; Mocciaro, Gabriele; Hahnefeld, Lisa; Lamichhane, Santosh; Fabritius, Mikael; Avela, Henri; Wang, Yuqin; Dickens, Alex M.; Gurke, Robert; Yang, Baoru; Griffiths, William J.; Hyötyläinen, Tuulia; Meikle, Peter J.; Orešič, Matej
    (    A2 Refereed review article in a scientific journal )


  • Perfluorooctanoic acid disrupts hepatic metabolism in the developing chicken embryo  (2025)  
    • Metabolomics
     Scherbak, Nikolai; Duberg, Daniel; Kråkström, Matilda; Tikka, Pauli; Dickens, Alex M.; Engwall, Magnus; Orešič, Matej; Hyötyläinen, Tuulia
    (    A1 Refereed original research article in a scientific journal)


  • Prenatal exposure to perfluoroalkyl substances predicts multimodal brain structural and functional outcomes in children aged 5 years: a birth cohort study  (2025)  
    • The Lancet Planetary Health
     Barron, Aaron; Dickens, Alex M; Tuulari, Jetro J; Hyötylainen, Tuulia; Kortesluoma, Susanna; Merisaari, Harri; Pulli, Elmo P; Silver, Eero; Kumpulainen, Venla; Copeland, Anni; Saukko, Ekaterina; Lewis, John D; Karlsson, Linnea; Orešič, Matej; Karlsson, Hasse
    (    A1 Refereed original research article in a scientific journal)


  • The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research  (2025)  
    • Analytical Chemistry
     Nguyen, Anh Hoang; Castro-Alves, Victor; Holmström, Flores Emilia; Barbosa, João Marcos G.; Kråkström, Matilda; Reinivuori, Päivikki; Kauko, Otto; Dickens, Alex; Orešič, Matej; Hyötyläinen, Tuulia
    (    A1 Refereed original research article in a scientific journal)


  • Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization  (2024)  
    • Analytical Chemistry
     Isokääntä Heidi, Pinto da Silva Lucas, Karu Naama, Kallonen Teemu, Aatsinki Anna-Katariina, Hankemeier Thomas, Schimmel Leyla, Diaz Edgar, Hyötyläinen Tuulia, Dorrestein Pieter C., Knight Rob, Orešič Matej, Kaddurah-Daouk Rima, Dickens Alex M., Lamichhane Santosh
    (    A1 Refereed original research article in a scientific journal)


  • Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards  (2024)  
    • Nature Communications
     Torta F., Hoffmann N., Burla B., Alecu I., Arita M., Bamba T., Bennett S.A.L., Bertrand-Michel J., Brügger B., Cala M.P., Camacho-Muñoz D., Checa A., Chen M., Chocholoušková M., Cinel M., Chu-Van E., Colsch B., Coman C., Connell L., Sousa B.C., Dickens A.M., Fedorova M., Eiríksson F.F., Gallart-Ayala H., Ghorasaini M., Giera M., Guan X.L., Haid M., Hankemeier T., Harms A., Höring M., Holčapek M., Hornemann T., Hu C., Hülsmeier A.J., Huynh K., Jones C.M., Ivanisevic J., Izumi Y., Köfeler H.C., Lam S.M., Lange M., Lee J.C., Liebisch G., Lippa K., Lopez-Clavijo A.F., Manzi M., Martinefski M.R., Math R.G.H., Mayor S., Meikle P.J., Monge M.E., Moon M.H., Muralidharan S., Nicolaou A., Nguyen-Tran T., O'Donnell V.B., Orešič M., Ramanathan A., Riols F., Saigusa D., Schock T.B., Schwartz-Zimmermann H., Shui G., Singh M., Takahashi M., Thorsteinsdóttir M., Tomiyasu N., Tournadre A., Tsugawa H., Tyrrell V.J., van der Gugten G., Wakelam M.O., Wheelock C.E., Wolrab D., Xu G., Xu T., Bowden J.A., Ekroos K., Ahrends R., Wen
    (    A1 Refereed original research article in a scientific journal)


  • Infant gut microbiota and negative and fear reactivity  (2024)  
    • Development and Psychopathology
     Huovinen, Venla; Aatsinki, Anna-Katariina; Kataja, Eeva-Leena; Munukka, Eveliina; Keskitalo, Anniina; Lamichhane, Santosh; Raunioniemi, Peppi; Bridgett, David J.; Lahti, Leo; O’Mahony, Siobhain M.; Dickens, Alex; Korja, Riikka; Karlsson, Hasse; Nolvi, Saara; Karlsson, Linnea
    (    A1 Refereed original research article in a scientific journal)


  • Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors  (2024)  
    • Metabolomics
     Cruz, Abraham Kuri; Alves, Marina Amaral; Andresson, Thorkell; Bayless, Amanda L.; Bloodsworth, Kent J.; Bowden, John A.; Bullock, Kevin; Burnet, Meagan C.; Carnevale Neto, Fausto; Choy, Angelina; Clish, Clary B.; Couvillion, Sneha P.; Cumeras, Raquel; Dailey, Lucas; Dallmann, Guido; Davis, W. Clay; Deik, Amy A.; Dickens, Alex M.; Djukovic, Danijel; Dorrestein, Pieter C.; Eder, Josie G.; Fiehn, Oliver; Flores, Roberto; Gika, Helen; Hagiwara, Kehau A.; Pham, Tuan Hai; Harynuk, James J.; Aristizabal-Henao, Juan J.; Hoyt, David W.; Jean-Francois, Focant; Krakstroem, Matilda; Kumar, Amit; Kyle, Jennifer E.; Lamichhane, Santosh; Li, Yuan; Nam, Seo Lin; Mandal, Rupasri; de la Mata, A. Paulina; Meehan, Michael J.; Meikopoulos, Thomas; Metz, Thomas O.; Mouskeftara, Thomai; Munoz, Nathalie; Gowda, G. A. Nagana; Orešic, Matej; Panitchpakdi, Morgan; Pierre-Hugues, Stefanuto; Raftery, Daniel; Rushing, Blake; Schock, Tracey; Seifried, Harold; Servetas, Stephanie; Shen, Tong; Sumner, Susan; Carrillo, Kieran S. Tarazona; Thibaut, Dejong; Trejo, Jesse B.; Van Meulebroek, Lieven; Vanhaecke, Lynn; Virgiliou, Christina; Weldon, Kelly C.; Wishart, David S.; Zhang, Lu; Zheng, Jiamin; Da Silva, Sandra
    (    A1 Refereed original research article in a scientific journal)


  • Novel Lipid Formulation Increases Absorption of Oral Cannabidiol (CBD)  (2024)  
    • Pharmaceutics
     Chesney, Edward; Mazibuko, Ndabezinhle; Oliver, Dominic; Minichino, Amedeo; Lamper, Ayse Doga; Chester, Lucy; Reilly, Thomas J.; Lloyd, Millie; Krakstrom, Matilda; Dickens, Alex M.; Oresic, Matej; Lynch, Eric; Stoloff, Gregory; Mehta, Mitul A.; Mcguire, Philip
    (    A1 Refereed original research article in a scientific journal)


  • Serum lipidome associates with neuroimaging features in patients with traumatic brain injury  (2024)  
    • iScience
     Thomas, Ilias; Newcombe, Virginia F.J.; Dickens, Alex M.; Richter, Sophie; Posti, Jussi P.; Maas, Andrew I.R.; Tenovuo, Olli; Hyötyläinen, Tuulia; Büki, András; Menon, David K.; Orešič, Matej
    (    A1 Refereed original research article in a scientific journal)


  • Changes in lipids and inflammation in adults with super-refractory status epilepticus on a ketogenic diet  (2023)  
    • Frontiers in Molecular Biosciences
     Dickens Alex M, Johnson Tory P, Lamichhane Santosh, Kumar Anupama, Pardo Carlos A, Gutierrez Erie G, Haughey Norman, Cervenka Mackenzie C
    (    A1 Refereed original research article in a scientific journal)


  • Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children  (2023)  
    • Frontiers in Endocrinology
     Lamichhane Santosh, Sen Partho, Dickens Alex M, Kråkström Matilda, Ilonen Jorma, Lempainen Johanna, Hyöty Heikki, Lahesmaa Riitta, Veijola Riitta, Toppari Jorma, Hyötyläinen Tuulia, Knip Mikael, Orešič Matej

    (    A1 Refereed original research article in a scientific journal)


  • Dynamics of the Lipidome in a Colon Simulator  (2023)  
    • Metabolites
     Kråkström Matilda, Dickens Alex M, Amaral Alves Marina, Forssten Sofia D, Ouwehand Arthur C, Hyötyläinen Tuulia, Orešič Matej, Lamichhane Santosh
    (    A1 Refereed original research article in a scientific journal)


  • Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial  (2023)  
    • Trials
     Laaksonen Mikael, Rinne Jaakko, Rahi Melissa, Posti Jussi P., Laitio Ruut, Kivelev Juri, Saarenpää Ilkka, Laukka Dan, Frösen Juhana, Ronkainen Antti, Bendel Stepani, Långsjö Jaakko, Ala-Peijari Marika, Saunavaara Jani, Parkkola Riitta, Nyman Mikko, Martikainen Ilkka K., Dickens Alex M., Rinne Juha, Valtonen Mika, Saari Teijo I., Koivisto Timo, Bendel Paula, Roine Timo, Saraste Antti, Vahlberg Tero, Tanttari Juha, Laitio Timo
    (    A1 Refereed original research article in a scientific journal)



Last updated on 12/07/2023 11:40:00 AM