Pauli Kallio
Ph.D.
pataka@utu.fi +358 29 450 4209 +358 50 339 6978 Itäinen Pitkäkatu 4 C Turku Office: 6038.1 ORCID identifier: https://orcid.org/0000-0003-3590-9882 |
Synthetic biology; Cyanobacterial metabolic engineering; Molecular biology; Enzymology
The research in our group (Synthetic Biology of Cyanobacteria) is focused on metabolic engineering and characterization of photosynthetic cyanobacteria. We aim to establish and use different synthetic biology approaches to enable more efficient metabolic engineering of the target strains. The ultimate objective is to develop novel biotechnological applications, which would allow solar-driven production of different carbon-based chemicals directly from CO2 – using photoautotrophic cyanobacterial cells as biological catalysts.
The research stems from the fundamental photosynthesis research carried out at Molecular Plant Biology, and covers different areas of molecular biology, microbiology and analytics.
Find more information on our group website at http://utu.fi/sbc
Microbial Metabolic Engineering
https://opas.peppi.utu.fi/fi/opintojakso/KABI4005/6626
Scientific Presentation Skills
https://opas.peppi.utu.fi/fi/opintojakso/KABI4003/6619
- Comparison of alternative integration sites in the chromosome and the native plasmids of the cyanobacterium Synechocystis sp. PCC 6803 in respect to expression efficiency and copy number (2021)
- Microbial Cell Factories
(Refereed journal article or data article (A1)) - Hydrocarbon Desaturation in Cyanobacterial Thylakoid Membranes Is Linked With Acclimation to Suboptimal Growth Temperatures (2021)
- Frontiers in Microbiology
(Refereed journal article or data article (A1)) - Photoautotrophic production of renewable ethylene by engineered cyanobacteria: Steering the cell metabolism towards biotechnological use (2021)
- Physiologia Plantarum
(Refereed journal article or data article (A1)) - Enhanced stable production of ethylene in photosynthetic cyanobacterium Synechococcus elongatus PCC 7942 (2019)
- World Journal of Microbiology and Biotechnology
(Refereed journal article or data article (A1)) - Redirecting photosynthetic electron flux in the cyanobacterium Synechocystis sp. PCC 6803 by the deletion of flavodiiron protein Flv3 (2019)
- Microbial Cell Factories
(Refereed journal article or data article (A1)) - Comparison of ethanol tolerance between potential cyanobacterial production hosts (2018)
- Journal of Biotechnology
(Refereed journal article or data article (A1)) - Translation efficiency of heterologous proteins is significantly affected by the genetic context of RBS sequences in engineered cyanobacterium Synechocystis sp PCC 6803 (2018)
- Microbial Cell Factories
(Refereed journal article or data article (A1)) - Comparison of orthologous cyanobacterial aldehyde deformylating oxygenases in the production of volatile C3-C7 alkanes in engineered E. coli (2017)
- Metabolic Engineering Communications
(Refereed journal article or data article (A1)) - Engineering the cyanobacterium synechocystis Sp. PCC 6803 towards optimized solutions for future biotechnological applications (2017) Nagy C., Aro E., Kallio P., Patrikainen P., Thiel K., Dandapani H., Mulaku E., Kakko L.
(Other (O2)) - Inactivation of iron-sulfur cluster biogenesis regulator SufR in Synechocystis sp. PCC 6803 induces unique iron-dependent protein-level responses (2017)
- BBA - General Subjects
(Refereed journal article or data article (A1)) - Pyridine nucleotide transhydrogenase PntAB is essential for optimal growth and photosynthetic integrity under low-light mixotrophic conditions in Synechocystis sp. PCC 6803 (2017)
- New Phytologist
(Refereed journal article or data article (A1)) - SRM dataset of the proteome of inactivated iron-sulfur cluster biogenesis regulator SufR in Synechocystis sp. PCC 6803 (2017)
- Data in Brief
(Refereed journal article or data article (A1)) - The effect of enhanced acetate influx on Synechocystis sp. PCC 6803 metabolism (2017)
- Microbial Cell Factories
(Refereed journal article or data article (A1)) - Development of a Quantitative SRM-Based Proteomics Method to Study Iron Metabolism of Synechocystis sp. PCC 6803 (2016)
- Journal of Proteome Research
(Refereed journal article or data article (A1)) - Sequence optimization of efegene from P. syringae is not required for stable ethylene production in recombinant Synechocystis sp. PCC6803. (2016)
- International Journal of Innovative Research in Technology and Science
(Refereed journal article or data article (A1)) - A microbial platform for renewable propane synthesis based on a fermentative butanol pathway (2015)
- Biotechnology for Biofuels
(Refereed journal article or data article (A1)) - A synthetic O2 -tolerant butanol pathway exploiting native fatty acid biosynthesis in Escherichia coli (2015)
- Biotechnology and Bioengineering
(Refereed journal article or data article (A1)) - An engineered pathway for the biosynthesis of renewable propane (2014)
- Nature Communications
(Refereed journal article or data article (A1)) - Engineering Photobiological H2-Production (2014) Algal Biorefineries Linda Vuorijoki, Pauli Kallio, Patrik R. Jones
(Refereed article in compilation book (A3)) - Renewable Jet Fuel (2014)
- Current Opinion in Biotechnology
(Refereed review article in scientific journal (A2))