Pauli Kallio
Ph.D.
pataka@utu.fi +358 29 450 4209 +358 50 339 6978 Itäinen Pitkäkatu 4 C Turku Office: 6038.1 ORCID identifier: https://orcid.org/0000-0003-3590-9882(external) |
Areas of expertise
Synthetic biology; Cyanobacterial metabolic engineering; Molecular biology; Enzymology
Synthetic biology; Cyanobacterial metabolic engineering; Molecular biology; Enzymology
Research community or research topic
Department of Life Technologies, Faculty of Technology
Department of Life Technologies, Faculty of Technology
Research
The research in our group (Synthetic Biology of Cyanobacteria) is focused on metabolic engineering and characterization of photosynthetic cyanobacteria. We aim to establish and use different synthetic biology approaches to enable more efficient metabolic engineering of the target strains. The ultimate objective is to develop novel biotechnological applications, which would allow solar-driven production of different carbon-based chemicals directly from CO2 – using photoautotrophic cyanobacterial cells as biological catalysts.
The research stems from the fundamental photosynthesis research carried out at Molecular Plant Biology, and covers different areas of molecular biology, microbiology and analytics.
Find more information on our group website at http://utu.fi/sbc(external)
Teaching
DIBT0603 Microbial Metabolic Engineering - Practice
DIBT0084-3001 Kestävien bioteknisten prosessien perusteet
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0084/87338(external)
DIBT0607-3001 Scientific Writing in Biosciences
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0607/91865(external)
DIBT0604-3001 Technology Outreach
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0604/88473(external)
https://sites.utu.fi/technologyoutreach(external)
DIBT0602 Microbial Metabolic Engineering I
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0602/89496(external)
DIBT0603 Microbial Metabolic Engineering - Practice
https://opas.peppi.utu.fi/fi/opintojakso/DIBT0603/89497(external)
Publications 
1 of 2
- Engineering RNA polymerase to construct biotechnological host strains of cyanobacteria (2024)
- Physiologia Plantarum
(A1 Refereed original research article in a scientific journal) - Interplay between photosynthetic electron flux and organic carbon sinks in sucrose-excreting Synechocystis sp PCC 6803 revealed by omics approaches (2024)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - A Plasmid-Based Fluorescence Reporter System for Monitoring Oxidative Damage in E. coli (2022)
- Sensors
(A1 Refereed original research article in a scientific journal) - Photosynthetically produced sucrose by immobilized Synechocystis sp. PCC 6803 drives biotransformation in E. coli (2022)
- Biotechnology for Biofuels and Bioproducts
(A1 Refereed original research article in a scientific journal) - Comparison of alternative integration sites in the chromosome and the native plasmids of the cyanobacterium Synechocystis sp. PCC 6803 in respect to expression efficiency and copy number (2021)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - Hydrocarbon Desaturation in Cyanobacterial Thylakoid Membranes Is Linked With Acclimation to Suboptimal Growth Temperatures (2021)
- Frontiers in Microbiology
(A1 Refereed original research article in a scientific journal) - Photoautotrophic production of renewable ethylene by engineered cyanobacteria: Steering the cell metabolism towards biotechnological use (2021)
- Physiologia Plantarum
(A1 Refereed original research article in a scientific journal) - Enhanced stable production of ethylene in photosynthetic cyanobacterium Synechococcus elongatus PCC 7942 (2019)
- World Journal of Microbiology and Biotechnology
(A1 Refereed original research article in a scientific journal) - Redirecting photosynthetic electron flux in the cyanobacterium Synechocystis sp. PCC 6803 by the deletion of flavodiiron protein Flv3 (2019)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - Comparison of ethanol tolerance between potential cyanobacterial production hosts (2018)
- Journal of Biotechnology
(A1 Refereed original research article in a scientific journal) - Translation efficiency of heterologous proteins is significantly affected by the genetic context of RBS sequences in engineered cyanobacterium Synechocystis sp PCC 6803 (2018)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - Comparison of orthologous cyanobacterial aldehyde deformylating oxygenases in the production of volatile C3-C7 alkanes in engineered E. coli (2017)
- Metabolic Engineering Communications
(A1 Refereed original research article in a scientific journal) - Engineering the cyanobacterium synechocystis Sp. PCC 6803 towards optimized solutions for future biotechnological applications (2017) Nagy C., Aro E., Kallio P., Patrikainen P., Thiel K., Dandapani H., Mulaku E., Kakko L.
(Other publication) - Inactivation of iron-sulfur cluster biogenesis regulator SufR in Synechocystis sp. PCC 6803 induces unique iron-dependent protein-level responses (2017)
- BBA - General Subjects
(A1 Refereed original research article in a scientific journal) - Pyridine nucleotide transhydrogenase PntAB is essential for optimal growth and photosynthetic integrity under low-light mixotrophic conditions in Synechocystis sp. PCC 6803 (2017)
- New Phytologist
(A1 Refereed original research article in a scientific journal) - SRM dataset of the proteome of inactivated iron-sulfur cluster biogenesis regulator SufR in Synechocystis sp. PCC 6803 (2017)
- Data in Brief
(A1 Refereed original research article in a scientific journal) - The effect of enhanced acetate influx on Synechocystis sp. PCC 6803 metabolism (2017)
- Microbial Cell Factories
(A1 Refereed original research article in a scientific journal) - Development of a Quantitative SRM-Based Proteomics Method to Study Iron Metabolism of Synechocystis sp. PCC 6803 (2016)
- Journal of Proteome Research
(A1 Refereed original research article in a scientific journal) - Sequence optimization of efegene from P. syringae is not required for stable ethylene production in recombinant Synechocystis sp. PCC6803. (2016)
- International Journal of Innovative Research in Technology and Science
(A1 Refereed original research article in a scientific journal) - A microbial platform for renewable propane synthesis based on a fermentative butanol pathway (2015)
- Biotechnology for Biofuels
(A1 Refereed original research article in a scientific journal)
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