A1 Refereed original research article in a scientific journal
A microbial platform for renewable propane synthesis based on a fermentative butanol pathway
Authors: Menon N, Pasztor A, Menon BRK, Kallio P, Fisher K, Akhtar MK, Leys D, Jones PR, Scrutton NS
Publisher: Biomed Central LTD
Publication year: 2015
Journal: Biotechnology for Biofuels
Journal name in source: BIOTECHNOLOGY FOR BIOFUELS
Journal acronym: Biotechnol biofuels
Article number: ARTN 61
Volume: 8
Issue: 6
Number of pages: 12
ISSN: 1754-6834
DOI: https://doi.org/10.1186/s13068-015-0231-1(external)
Web address : http://www.biotechnologyforbiofuels.com/content/8/1/61(external)
Conclusions: This study expands the metabolic toolbox for renewable propane production and provides new insight and understanding for the development of next-generation biofuel platforms. In developing an alternative CoA-dependent fermentative butanol pathway, which includes an engineered ADO variant (ADO(A134F)), the study addresses known limitations, including the low bio-availability of butyraldehyde precursors and poor activity of ADO with butyraldehyde.