Matej Oresic
Ph.D.
matej.oresic@utu.fi +358 29 450 3798 +358 46 923 3395 Tykistökatu 6 Turku ORCID-tunniste: https://orcid.org/0000-0002-2856-9165 |
Systems biology, exposome, bioinformatics, metabolomics, lipidomics, biophysics, systems medicine, computational biology
Professor Matej Orešič holds a PhD in biophysics from Cornell University (1999; Ithaca, NY, USA). He is professor of medicine, with specialization in systems medicine at Örebro University (Sweden) and a professor of biochemistry (metabolomics) at the University of Turku (Finland). Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. As of 2016, he was made a Lifetime Honorary Fellow of the Metabolomics Society. Professor Orešič currently serves as member of the Board of Directors of the Metabolomics Society and is one of the founders of the Nordic Metabolomics Society, previously serving as its chair of the board. In 2019, he co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA). Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
Professor Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
- Does cannabidiol reduce the adverse effects of cannabis in schizophrenia? A randomised, double-blind, cross-over trial (2025)
- NeuropsychopharmacologyDiabetologia
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - (2025)
- iScience
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - 2025
- Trends in Analytical Chemistry
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Metabolome informs about the chemical exposome and links to brain health (2025)
- Journal of Chromatography AThe Lancet Planetary Health
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - 2025
- Environment International
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä) - Perfluorooctanoic acid disrupts hepatic metabolism in the developing chicken embryoIdentification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease (2025)
- Metabolomics
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - 2025
- The Lancet Planetary HealthAnalytical Chemistry
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - (2025)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Comparative Metabolomics and Microbiome Analysis of Ethanol versus OMNImet/gene•GUT Fecal Stabilization (2024)
- Analytical ChemistryEnvironment International
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - 2024
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Exposure to environmental toxicants is associated with gut microbiome dysbiosis, insulin resistance and obesity (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Hepatic glucose production is increased in MASH with significant fibrosis even in absence of diabetes (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis (2024)
- Cell Reports MedicineEnvironmental Science and TechnologyCell
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - 2024
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Impact of Environmental Exposures on Human Breast Milk Lipidome in Future Immune-Mediated Diseases (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Infant microbes and metabolites point to childhood neurodevelopmental disorders (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4+ regulatory T cells by regulating IL2RA (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - 2024
- Proceedings of the National Academy of Sciences of the United States of AmericaEnvironment International
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models (2024)
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors (2024)
- Metabolomics
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )



