Matej Oresic
Ph.D.
matej.oresic@utu.fi +358 29 450 3798 +358 46 923 3395 Tykistökatu 6 Turku ORCID identifier: https://orcid.org/0000-0002-2856-9165 |
Systems biology, exposome, bioinformatics, metabolomics, lipidomics, biophysics, systems medicine, computational biology
Professor Matej Orešič holds a PhD in biophysics from Cornell University (1999; Ithaca, NY, USA). He is professor of medicine, with specialization in systems medicine at Örebro University (Sweden) and a professor of biochemistry (metabolomics) at the University of Turku (Finland). Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. As of 2016, he was made a Lifetime Honorary Fellow of the Metabolomics Society. Professor Orešič currently serves as member of the Board of Directors of the Metabolomics Society and is one of the founders of the Nordic Metabolomics Society, previously serving as its chair of the board. In 2019, he co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA). Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
Professor Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.
- (2019)
- JCI Insight
(A1 Refereed original research article in a scientific journal) - Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children (2019)
- Biological PsychiatryMetabolites
(A1 Refereed original research article in a scientific journal) - (2019)
- Trends in Analytical Chemistry
(A1 Refereed original research article in a scientific journal) - (2019)
- MetabolitesFrontiers in Molecular Biosciences
(A2 Refereed review article in a scientific journal ) - Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS) (2019)
(A1 Refereed original research article in a scientific journal) - Persistent Alterations in Plasma Lipid Profiles Before Introduction of Gluten in the Diet Associated With Progression to Celiac Disease (2019)
- Clinical and Translational Gastroenterology
(A1 Refereed original research article in a scientific journal) - (2019)
- Analytical and Bioanalytical Chemistry
(A1 Refereed original research article in a scientific journal) - (2019)
- Metabolites
(A1 Refereed original research article in a scientific journal) - The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort StudiesAnalysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response (2019)
- American Journal of Epidemiology
(A1 Refereed original research article in a scientific journal) - The Role of Omic Technologies in the Study of the Human Gut Microbiome (2019) Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
(A3 Refereed book chapter or chapter in a compilation book) - A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links (2018)
- Nature Protocols
(A1 Refereed original research article in a scientific journal) - A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes (2018)
- Scientific Data
(A1 Refereed original research article in a scientific journal) - (2018)
- Schizophrenia ResearchJournal of Lipid Research
(A1 Refereed original research article in a scientific journal) - Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP) (2018)
- Scientific Reports
(A1 Refereed original research article in a scientific journal) - (2018)
- Methods
(A1 Refereed original research article in a scientific journal) - (2018)
- MetabolismDiabetes Care
(A1 Refereed original research article in a scientific journal) - MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines (2018)
(A1 Refereed original research article in a scientific journal) - Perspectives on systems modeling of human peripheral blood mononuclear cells (2018)
(A2 Refereed review article in a scientific journal ) - Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project (2018)
- European Psychiatry
(A2 Refereed review article in a scientific journal ) - Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars (2018)
(A1 Refereed original research article in a scientific journal)



