Matej Oresic
 Ph.D.


matej.oresic@utu.fi

+358 29 450 3798

+358 46 923 3395

Tykistökatu 6

Turku


ORCID identifierhttps://orcid.org/0000-0002-2856-9165

Systems Medicine group

Google Scholar



Areas of expertise
Systems biology, exposome, bioinformatics, metabolomics, lipidomics, biophysics, systems medicine, computational biology

Biography

Professor Matej Orešič holds a PhD in biophysics from Cornell University (1999; Ithaca, NY, USA). He is professor of medicine, with specialization in systems medicine at Örebro University (Sweden) and a professor of biochemistry (metabolomics) at the University of Turku (Finland). Prof. Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. As of 2016, he was made a Lifetime Honorary Fellow of the Metabolomics Society. Professor Orešič currently serves as member of the Board of Directors of the Metabolomics Society and is one of the founders of the Nordic Metabolomics Society, previously serving as its chair of the board. In 2019, he co-chaired the 1st Gordon Research Conference on ‘Metabolomics and Human Health’ (Ventura, CA, USA). Previously, he also chaired the Keystone Symposium on Systems Biology of Lipid Metabolism (2015; Breckenridge, CO, USA). Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.



Research

Professor Orešič’s main research areas include exposomics and metabolomics applications in biomedical research and systems medicine. He is particularly interested in the identification of environmental exposures (exposome) and disease processes associated with different metabolic phenotypes and the underlying mechanisms linking these processes with the development of specific disorders or their co-morbidities. Prof. Orešič also initiated the popular MZmine open-source project, which led to the development and release of popular software for metabolomics data processing. Professor Orešič currently coordinates Horizon Europe project “Inflammation in human early life: targeting impacts on life-course health – INITIALISE (https://initialise-project.eu/)”. He is also Co-Coordinator of the new Horizon Europe project “Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease – EDC-MASLD (https://edc-masld.eu/)”.



Publications
  
Go to first page
  
Go to previous page
  
6 of 9
  
Go to next page
  
Go to last page
  

  •   (2019)  
    • JCI Insight
     Panu K. Luukkonen, Auli Nick, Maarit Hölttä-Vuori, Christoph Thiele, Elina Isokuortti, Susanna Lallukka-Brück, You Zhou, Antti Hakkarainen, Nina Lundbom, Markku Peltonen, Marju Orho-Melander, Matej Orešič, Tuulia Hyötyläinen, Leanne Hodson, Elina Ikonen, Hannele Yki-Järvinen
    (
    A1 Refereed original research article in a scientific journal)


  • Integrated Lipidomics and Proteomics Point to Early Blood-Based Changes in Childhood Preceding Later Development of Psychotic Experiences: Evidence From the Avon Longitudinal Study of Parents and Children  (2019)  
    • Biological PsychiatryMetabolites
     Madrid-Gambin F., Föcking M., Sabherwal S., Heurich M., English J., O'Gorman A., Suvitaival T., Ahonen L., Cannon M., Lewis G., Mattila I., Scaife C., Madden S., Hyötyläinen T., Orešič M., Zammit S., Cagney G., Cotter D., Brennan L.
    (
    A1 Refereed original research article in a scientific journal)


  •   (2019)  
    • Trends in Analytical Chemistry
     Fang Wei, Santosh Lamichhane, Matej Orešič, Tuulia Hyötyläinen
    (
    A1 Refereed original research article in a scientific journal)


  •   (2019)  
    • MetabolitesFrontiers in Molecular Biosciences
     Partho Sen, Matej Orešič
    (
    A2 Refereed review article in a scientific journal )


  • Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS)  (2019)  
       Mary C. Playdon, Amit D. Joshi, Fred K. Tabung, Susan Cheng, Mir Henglin, Andy Kim, Tengda Lin, Eline H. van Roekel, Jiaqi Huang, Jan Krumsiek, Ying Wang, Ewy Mathé, Marinella Temprosa, Steven Moore, Bo Chawes, A. Heather Eliassen, Andrea Gsur, Marc J. Gunter, Sei Harada, Claudia Langenberg, Matej Oresic, Wei Perng, Wei Jie Seow, Oana A. Zeleznik
      (
      A1 Refereed original research article in a scientific journal)


    • Persistent Alterations in Plasma Lipid Profiles Before Introduction of Gluten in the Diet Associated With Progression to Celiac Disease  (2019)  
      • Clinical and Translational Gastroenterology
       Sen P, Carlsson C, Virtanen SM, Simell S, Hyöty H, Ilonen J, Toppari J, Veijola R, Hyötyläinen T, Knip M, Orešič M
      (
      A1 Refereed original research article in a scientific journal)


    •   (2019)  
      • Analytical and Bioanalytical Chemistry
       Samira Salihović, Alex M. Dickens, Ida Schoultz, Frida Fart, Lisanna Sinisalu, Tuomas Lindeman, Jonas Halfvarson, Matej Orešič, Tuulia Hyötyläinen
      (
      A1 Refereed original research article in a scientific journal)


    •   (2019)  
      • Metabolites
       Ahonen L, Jäntti S, Suvitaival T, Theilade S, Risz C, Kostiainen R, Rossing P, Oresic M, Hyötyläinen T
      (
      A1 Refereed original research article in a scientific journal)


    • The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort StudiesAnalysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response  (2019)  
      • American Journal of Epidemiology
       Bing Yu, Krista A Zanetti, Marinella Temprosa, Demetrius Albanes, Nathan Appel, Clara Barrios Barrera, Yoav Ben-Shlomo, Eric Boerwinkle, Juan P Casas, Clary Clish, Caroline Dale, Abbas Dehghan, Andriy Derkach, A Heather Eliassen, Paul Elliott, Eoin Fahy, Christian Gieger, Marc J Gunter, Sei Harada, Tamara Harris, Deron R Herr, David Herrington, Joel N Hirschhorn, Elise Hoover, Ann W Hsing, Mattias Johansson, Rachel S Kelly, Chin Meng Khoo, Mika Kivimäki, Bruce S Kristal, Claudia Langenberg, Jessica Lasky-Su, Deborah A Lawlor, Luca A Lotta, Massimo Mangino, Loïc Le Marchand, Ewy Mathé, Charles E Matthews, Cristina Menni, Lorelei A Mucci, Rachel Murphy, Matej Oresic, Eric Orwoll, Jennifer Ose, Alexandre C Pereira, Mary C Playdon, Lucilla Poston, Jackie Price, Qibin Qi, Kathryn Rexrode, Adam Risch, Joshua Sampson, Wei Jie Seow, Howard D Sesso, Svati H Shah, Xiao-Ou Shu, Gordon C S Smith, Ulla Sovio, Victoria L Stevens, Rachael Stolzenberg-Solomon, Toru Takebayashi, Therese Tillin, Ruth Travis, Ioanna Tzoulaki, Cornelia M Ulrich, Ramachandran S Vasan, Mukesh Verma, Ying Wang, Nick J Wareham, Andrew Wong, Naji Younes, Hua Zhao, Wei Zheng, Steven C Moore
      (
      A1 Refereed original research article in a scientific journal)


    • The Role of Omic Technologies in the Study of the Human Gut Microbiome  (2019)  Reference Module in Food Science Partho Sen, Santosh Lamichhane, Alex M Dickens, Matej Orešič
      (
      A3 Refereed book chapter or chapter in a compilation book)


    • A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links  (2018)  
      • Nature Protocols
       Helle Krogh Pedersen, Sofia K. Forslund, Valborg Gudmundsdottir, Anders Østergaard Petersen, Falk Hildebrand, Tuulia Hyötyläinen, Trine Nielsen, Torben Hansen, Peer Bork, S. Dusko Ehrlich, Søren Brunak, Matej Oresic, Oluf Pedersen, Henrik Bjørn Nielsen
      (
      A1 Refereed original research article in a scientific journal)


    • A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes  (2018)  
      • Scientific Data
       Lamichhane S, Ahonen L, Dyrlund TS, Siljander H, Hyöty H, Ilonen J, Toppari J, Veijola R, Hyötyläinen T, Knip M, Orešič M
      (
      A1 Refereed original research article in a scientific journal)


    •   (2018)  
      • Schizophrenia ResearchJournal of Lipid Research
       Schwarz E, Maukonen J, Hyytiainen T, Kieseppa T, Oresic M, Sabunciyan S, Mantere O, Saarela M, Yolken R, Suvisaari J
      (
      A1 Refereed original research article in a scientific journal)


    • Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP)  (2018)  
      • Scientific Reports
       Santosh Lamichhane, Linda Ahonen, Thomas Sparholt Dyrlund, Esko Kemppainen, Heli Siljander, Heikki Hyöty, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Tuulia Hyötyläinen, Mikael Knip, Matej Oresic
      (
      A1 Refereed original research article in a scientific journal)


    •   (2018)  
      • Methods
       Santosh Lamichhane, Partho Sen, Alex M.Dickens, Matej Orešič, Hanne Christine Bertram
      (
      A1 Refereed original research article in a scientific journal)


    •   (2018)  
      • MetabolismDiabetes Care
       Tommi Suvitaival, Isabel Bondia-Pons, Laxman Yetukuri, Päivi Pöhö, John J. Nolan, Tuulia Hyötyläinen, Johanna Kuusisto, Matej Orešič
      (
      A1 Refereed original research article in a scientific journal)


    • MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines  (2018)  
         Bo Burla, Makoto Arita, Masanori Arita, Anne K. Bendt, Amaury Cazenave-Gassiot, Edward A. Dennis, Kim Ekroos, Xianlin Han, Kazutaka Ikeda, Gerhard Liebisch, Michelle K. Lin, Tze Ping Loh, Peter J. Meikle, Matej Orešič, Oswald Quehenberger, Andrej Shevchenko, Federico Torta, Michael J. O. Wakelam, Craig E. Wheelock, Markus R. Wenk
        (
        A1 Refereed original research article in a scientific journal)


      • Perspectives on systems modeling of human peripheral blood mononuclear cells  (2018)  
           Partho Sen, Esko Kemppainen, Matej Orešič
          (
          A2 Refereed review article in a scientific journal )


        • Platform for systems medicine research and diagnostic applications in psychotic disorders-The METSY project  (2018)  
          • European Psychiatry
           Elisabeth Frank, Dieter Maier, Juha Pajula, Tommi Suvitaival, Faith Borgan, Markus Butz-Ostendorf, Alexander Fischer, Jarmo Hietala, Oliver Howes, Tuulia Hyötyläinen, Joost Janssen, Heikki Laurikainen, Carmen Moreno, Jaana Suvisaari, Mark Van Gils, Matej Orešič
          (
          A2 Refereed review article in a scientific journal )


        • Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars  (2018)  
             Luukkonen PK, Sadevirta S, Zhou Y, Kayser B, Ali A, Ahonen L, Lallukka S, Pelloux V, Gaggini M, Jian C, Hakkarainen A, Lundbom N, Gylling H, Salonen A, Oresic M, Hyotylainen T, Orho-Melander M, Rissanen A, Gastaldelli A, Clement K, Hodson L, Yki-Jarvinen H
            (
            A1 Refereed original research article in a scientific journal)



          Last updated on 11/06/2025 04:19:35 PM