Luis Machado Crisóstomo
Postdoctoral researcher
luis.crisostomo@utu.fi : 4059 |
Luís Crisóstomo completed his BSc and his MSc on Biomedical Sciences at the University of Beira Interior, in Covilhã, Portugal. After his MSc, he worked as Software Engineer in a multinational Consulting company based in Lisbon, Portugal. In 2016, Luís returned to Fundamental Research and joined the Sertoli Cell & Gameta Biology research group, led by Prof. Marco G. Alves and Prof. Pedro F. Oliveira, at ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal. In 2017, Luís started his PhD "Paternally-induced transgenerational effects of high-fat diets" after obtaining a 4-year doctoral grant by FCT - The Portuguese Foundation for Science and Technology. During his PhD, Luís studied the transgenerational effects of high-fat diet in metabolic and reproductive function of non-exposed progeny.
In 2022, Luís joined Mildner´s group at InFlames, UTU, to further explore the role of lipidome in inflammation in the context of high-fat diet and excess adiposity.
- Homeostatic Functions of Tissue-Resident Macrophages and Their Role in Tissue Maintenance (2024) Monocytes and Macrophages in Development, Regeneration, and Disease Crisóstomo, Luís; Parena, Ae; Hyseni, Besmir; Bergman, Hans; Mildner, Alexander
- Mechanisms of thyrotropin receptor-mediated phenotype variability deciphered by gene mutations and M453T-knockin model (2024)
- JCI Insight
- A systematic scientometric review of paternal inheritance of acquired metabolic traits (2023)
- BMC Biology
- Metabolomics Integration in Assisted Reproductive Technologies for Enhanced Embryo Selection beyond Morphokinetic Analysis (2023)
- International Journal of Molecular Sciences
- Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery (2023)
- Obesity Surgery
- Comprehensive Analysis of Global Research on Human Varicocele: A Scientometric Approach (2022)
- The world journal of men's health
- Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis (2022)
- The world journal of men's health
- Inherited Metabolic Memory of High-Fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters (2022)
- Molecular Nutrition and Food Research
- Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects (2022)
- Animal Reproduction Science
- Testicular "Inherited Metabolic Memory" of Ancestral High-Fat Diet Is Associated with Sperm sncRNA Content (2022)
- Biomedicines
- Ancestral paternal exposure to high-fat diets causes testicular metabolic and functional disturbances in mice up to two generations (2021)
- FEBS Open Bio
- Inheritable testicular metabolic memory of high-fat diet causes transgenerational sperm defects in mice (2021)
- Scientific Reports
- Sperm, metabolic memory and echoes from Lamarck (2021)
- European Journal of Clinical Investigation
- Diet during early life defines testicular lipid content and sperm quality in adulthood (2020)
- American Journal of Physiology : Endocrinology and Metabolism
- Lifestyle, metabolic disorders and male hypogonadism - A one-way ticket? (2020)
- Molecular and Cellular Endocrinology
- Metabolic diseases affect male reproduction and induce signatures in gametes that may compromise the offspring health (2020)
- Environmental epigenetics
- Permanent testicular metabolomic and lipidomic signatures induced by the adoption of a high-fat diet in childhood and sperm quality in adulthood (2020)
- Human Reproduction
- A new thiocyanoacetamide (2-cyano-2-p-nitrophenyl-N-benzylthioamide) reduces doxorubicin-induced in vitro toxicity in Sertoli cells by decreasing apoptosis and autophagy (2019)
- Theriogenology
- A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome (2019)
- Reproduction
- High-fat diet compromises male fertility that is not surpassed by reversion to a controlled diet (2018)
- FEBS Open Bio