Kari Laine - UTU Research Portal - UTU Research Portal

Kari Laine

- Docent,
Faculty of Medicine (University of Turku)

karlai@utu.fi

Publications

Development and pilot testing of PHARAO—a decision support system for pharmacological risk assessment in the elderly (2018)
- European Journal of Clinical PharmacologyResearch in Social and Administrative Pharmacy
Andersson M., Böttiger Y., Laine K., Korhonen T., Lähdesmäki J., Shemeikka T., Julander M., Edlert M.
(A1 Refereed original research article in a scientific journal)
Voriconazole greatly increases the exposure to oral buprenorphineRifampicin decreases exposure to sublingual buprenorphine in healthy subjects (2018)
- European Journal of Clinical PharmacologyPharmacology Research and Perspectives
Mari Fihlman, Tuija Hemmilä, Nora M. Hagelberg, Janne T. Backman, Jouko Laitila, Kari Laine, Pertti J. Neuvonen, Klaus T. Olkkola, Teijo I. Saari
(A1 Refereed original research article in a scientific journal)
Identifying high risk medications causing potential drug-drug interactions in outpatients: A prescription database study based on an online surveillance systemVoriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction2016
T.M.Toivo, J.A.V. Mikkola, K. Laine, M. Airaksinen
(A1 Refereed original research article in a scientific journal)
(2016)
Hagelberg Nora M, Fihlman M, Hemmilä Tuija, Backman Janne T, Neuvonen Pertti J, Laine Kari, Olkkola Klaus T, Saari Teijo
(A1 Refereed original research article in a scientific journal)
Epidemiology of CYP3A4-Mediated Clopidogrel Drug-Drug Interactions and Their Clinical Consequences (2016)
- European Journal of Clinical Pharmacology
Fihlman M, Hemmila T, Hagelberg NM, Kuusniemi K, Backman JT, Laitila J, Laine K, Neuvonen PJ, Olkkola KT, Saari TI
(A1 Refereed original research article in a scientific journal)
Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadolRifampicin has a Profound Effect on the Pharmacokinetics of Oral S-Ketamine and Less on Intravenous S-Ketamine (2015)
- European Journal of Clinical Pharmacology
Saarikoski T, Saari TI, Hagelberg NM, Backman JT, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K
(A1 Refereed original research article in a scientific journal)
The degree of fetal metformin exposure does not influence fetal outcome in gestational diabetes mellitusS-ketamine concentrations are greatly increased by grapefruit juice (2014)
- Acta Diabetologica
Kristiina Tertti, Kari Laine, Ulla Ekblad, Valtteri Rinne, Tapani RönnemaaA1 Refereed original research article in a scientific journal
(2013)
- Cardiovascular Therapeutics
Tirkkonen T, Heikkila P, Vahlberg T, Huupponen R, Laine K
(A1 Refereed original research article in a scientific journal)
2012
- Basic and Clinical Pharmacology and Toxicology. Supplement
Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Kurkinen KJ, Neuvonen PJ, Olkkola KTA1 Refereed original research article in a scientific journal
(2012)
- European Journal of Clinical Pharmacology
Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Neuvonen PJ, Olkkola KT
(A1 Refereed original research article in a scientific journal)
St John's wort greatly decreases the plasma concentrations of oral S-ketamine (2012)
- Fundamental and Clinical Pharmacology
Peltoniemi MA, Saari TI, Hagelberg NM, Laine K, Neuvonen PJ, Olkkola KTA1 Refereed original research article in a scientific journal
Effect of Inhibition of Cytochrome P450 Enzymes 2D6 and 3A4 on the Pharmacokinetics of Intravenous Oxycodone A Randomized, Three-Phase, Crossover, Placebo-Controlled Study (2011)
- Clinical Drug Investigation
Gronlund J, Saari TI, Hagelberg NM, Neuvonen PJ, Laine K, Olkkola KT
(A1 Refereed original research article in a scientific journal)
Exposure to Oral S-ketamine Is Unaffected by Itraconazole but Greatly Increased by Ticlopidine (2011)
- Clinical Pharmacology and Therapeutics
Peltoniemi MA, Saari TI, Hagelberg NM, Reponen P, Turpeinen M, Laine K, Neuvonen PJ, Olkkola KT
(A1 Refereed original research article in a scientific journal)
Miconazole Oral Gel Increases Exposure to Oral Oxycodone by Inhibition of CYP2D6 and CYP3A4 (2011)
- Antimicrobial Agents and Chemotherapy
Gronlund J, Saari TI, Hagelberg N, Neuvonen PJ, Olkkola KT, Laine K
(A1 Refereed original research article in a scientific journal)
Potential CYP2C9-mediated drug-drug interactions in hospitalized type 2 diabetes mellitus patients treated with the sulphonylureas glibenclamide, glimepiride or glipizide (2010)
- Journal of Internal Medicine
Tirkkonen T, Heikkilä P, Huupponen R, Laine K
(A1 Refereed original research article in a scientific journal)