MD, PhD, Professor Emeritus Mika Scheinin - UTU Research Portal

Mika Scheinin
MD, PhD, Professor Emeritus

Institute of Biomedicine (Faculty of Medicine)

mschein@utu.fi

ORCID identifier: https://orcid.org/0000-0001-7579-9126

Areas of expertise

Bioanalytics; Clinical Pharmacology; Drug Development; Positron Emission Tomography; Research Ethics

Publications

11 of 13

A polymorphism in the protein kinase C gene PRKCB is associated with alpha(2)-adrenoceptor-mediated vasoconstriction (2013)
- Pharmacogenetics and Genomics
Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A
(A1 Refereed original research article in a scientific journal)
Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene (2013)
- Biopharmaceutics and Drug Disposition
Lehtinen T, Tolonen A, Turpeinen M, Uusitalo J, Vuorinen J, Lammintausta R, Pelkonen O, Scheinin M
(A1 Refereed original research article in a scientific journal)
Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo (2013)
- International Journal of Molecular Sciences
Turpeinen M, Uusitalo J, Lehtinen T, Kailajarvi M, Pelkonen O, Vuorinen J, Tapanainen P, Stjernschantz C, Lammintausta R, Scheinin M
(A1 Refereed original research article in a scientific journal)
Inhibition of alpha-adrenergic tone disturbs the distribution of blood flow in the exercising human limb (2013)
- AJP - Regulatory, Integrative and Comparative Physiology
Heinonen I, Wendelin-Saarenhovi M, Kaskinoro K, Knuuti J, Scheinin M, Kalliokoski KK
(A1 Refereed original research article in a scientific journal)
Lääkeaineiden vaikutusmekanismit – Reseptorit (2013) Farmakologia ja toksikologia Scheinin M
(A3 Refereed book chapter or chapter in a compilation book)
Longitudinal Amyloid Imaging in Mouse Brain with C-11-PIB: Comparison of APP23, Tg2576, and APP(swe)-PS1(dE9) Mouse Models of Alzheimer Disease (2013)
- Journal of Nuclear Medicine
Snellman A, Lopez-Picon FR, Rokka J, Salmona M, Forloni G, Scheinin M, Solin O, Rinne JO, Haaparanta-Solin M
(A1 Refereed original research article in a scientific journal)
Oral bioavailability of ospemifene improves with food intake (2013)
- International Journal of Clinical Pharmacology and Therapeutics
Koskimies P, Katila K, Lammintausta R, Aaltonen AM, Vuorinen J, Saarni O, Scheinin M
(A1 Refereed original research article in a scientific journal)
Plasma drug concentrations and clinical effects of a peripheral alpha-2-adrenoceptor antagonist, MK-467, in horses sedated with detomidine (2013)
- Veterinary Anaesthesia and Analgesia
Vainionpaa MH, Raekallio MR, Pakkanen SAE, Ranta-Panula V, Rinne VM, Scheinin M, Vainio OM
(A1 Refereed original research article in a scientific journal)
Rifampicin markedly decreases the exposure to oral and intravenous tramadol (2013)
- European Journal of Clinical Pharmacology
Saarikoski T, Saari TI, Hagelberg NM, Neuvonen M, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K
(A1 Refereed original research article in a scientific journal)
Single-dose and steady-state pharmacokinetics of ospemifene, a selective estrogen receptor modulator, in postmenopausal women (2013)
- International Journal of Clinical Pharmacology and Therapeutics
Koskimies P, Turunen J, Lammintausta R, Scheinin M
(A1 Refereed original research article in a scientific journal)
Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction (2013)
- European Journal of Clinical Pharmacology
Hagelberg NM, Saarikoski T, Saari TI, Neuvonen M, Neuvonen PJ, Turpeinen M, Scheinin M, Laine K, Olkkola KT
(A1 Refereed original research article in a scientific journal)
Tietoruutu L2 – Lääkeaineiden sitoutuminen reseptoriin (2013) Farmakologia ja toksikologia Scheinin M
(A3 Refereed book chapter or chapter in a compilation book)
Variation in the alpha(2A) adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose (2013)
- Pharmacogenetics and Genomics
Ghimire LV, Muszkat M, Sofowora GG, Scheinin M, Wood AJJ, Stein CM, Kurnik D
(A1 Refereed original research article in a scientific journal)
Adrenoseptoriagonistit (sympatomimeetit) (2012) Farmakologia ja toksikologia Scheinin Mika
(A3 Refereed book chapter or chapter in a compilation book)
Clinical research and clinical trials in the Region of South‐West Finland (2012) Scheinin Mika
(B3 Non-refereed article in a conference publication)
CYP2A6 genetic variation and dexmedetomidine disposition. (2012)
- European Journal of Clinical Pharmacology
Kohli Utkarsh, Pandharipande Pratik, Muszkat Mordechai, Soforowa Gbenga G, Friedman Eitan A, Scheinin Mika, Wood Alastair J J, Ely E Wesley, Tyndale Rachel F, Choi Leena, Stein C Michael, Kurnik Daniel
(A1 Refereed original research article in a scientific journal)
Dexmedetomidine decreases serum insulin concentrations and this response is influenced by alpha2a adrenoceptor genetic variation (2012)
- Clinical Pharmacology and Therapeutics
Ghimire LV, Kurnik D, Muszkat M, Sofowora GG, Scheinin M, Wood AJ, Stein C
(Other publication)
Effect of Immunotherapy With Bapineuzumab on Cerebrospinal Fluid Biomarker Levels in Patients With Mild to Moderate Alzheimer Disease (2012)
- Archives of Neurology -Chigago-
Blennow K, Zetterberg H, Rinne JO, Salloway S, Wei J, Black R, Grundman M, Liu E, AAB-001 201/202 Investigators (incl. Scheinin M)
(A1 Refereed original research article in a scientific journal)
G-proteiinikytkentäiset reseptorit merenkulun palveluksessa: stressilääkkeen uusi käyttöaihe (2012)
- Sphinx
Scheinin Mika
(B1 Non-refereed article in a scientific journal)
High-throughput screening with a miniaturized radioligand competition assay identifies new modulators of human α2-adrenoceptors. (2012)
- European Journal of Pharmaceutical Sciences
Fallarero Adyary, Pohjanoksa Katariina, Wissel Gloria, Parkkisenniemi-Kinnunen Ulla-Mari, Xhaard Henri, Scheinin Mika, Vuorela Pia
(A1 Refereed original research article in a scientific journal)