A1 Refereed original research article in a scientific journal

A polymorphism in the protein kinase C gene PRKCB is associated with alpha(2)-adrenoceptor-mediated vasoconstriction



Authors: Posti JP, Salo P, Ruohonen S, Valve L, Muszkat M, Sofowora GG, Kurnik D, Stein CM, Perola M, Scheinin M, Snapir A

Publisher: LIPPINCOTT WILLIAMS & WILKINS

Publication year: 2013

Journal: Pharmacogenetics and Genomics

Journal name in source: PHARMACOGENETICS AND GENOMICS

Journal acronym: PHARMACOGENET GENOM

Number in series: 3

Volume: 23

Issue: 3

First page : 127

Last page: 134

Number of pages: 8

ISSN: 1744-6872

DOI: https://doi.org/10.1097/FPC.0b013e32835d247f


Abstract
Conclusion Genetic variation in protein kinase C type beta may contribute toward the interindividual variation in DHV constriction responses to alpha(2)-AR activation by the agonist dexmedetomidine. Pharmacogenetics and Genomics 23:127-134 (c) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.



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