Ilkka Paatero
Ph.D.
ilanpa@utu.fi +358 29 450 3789 Tykistökatu 6 Turku ORCID-tunniste: https://orcid.org/0000-0001-5926-2396 |
cancer; cardiovascular biology; toxicology; microscopy; zebrafish models; model organisms;
My research covers broad range of topics in biomedicine. Current work is dealing mainly with cancer and cardiovascular biology.
My expertise is in application of model organisms, especially zebrafish (Danio rerio),
in biomedical research. These models can help to understand and solve
biomedical problems efficiently and ethically. Especially, when combined
with high-resolution intravital microscopy, these models can give deep
insights into developmental and disease processes in vivo. By using fish
eggs and embryos, it is also possible to reduce the number of more
complex and developed organisms used in research. These models, however, require certain set of skills and knowledge which is not part of the training of most medical and biomedical scientist. To facilite them to utilize the power of zebrafish models to advance their research, I have established a Zebrafish Core under Turku Centre for Biotechnology (University of Turku and Åbo Akademi University).
- GGA2 and RAB13 promote activity-dependent β1-integrin recycling (2019)
- Journal of Cell Science
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Helppokäyttöinen seeprakala tutkijan apuna (2019)
- Solubiologi
(D1 Artikkeli ammattilehdessä) - SORLA regulates endosomal trafficking and oncogenic fitness of HER2 (2019)
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction (2018)
- Nature Communications
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation (2018)
- eLife
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target (2018)
- BMC Cardiovascular Disorders
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Zebrafish Embryo Xenograft and Metastasis Assay (2018)
- Bio-protocol
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface- functionalization controlled penetrance of biological membranes (2017)
- Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - FiloQuant reveals increased filopodia density during breast cancer progression (2017)
- Journal of Cell Biology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä ) - Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts (2015)
- PLoS ONE
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )



