Ilkka Paatero
Ph.D.
ilanpa@utu.fi +358 29 450 3789 Tykistökatu 6 Turku |
cancer; cardiovascular biology; toxicology; microscopy; zebrafish models; model organisms;
My research covers broad range of topics in biomedicine. Current work is dealing mainly with cancer and cardiovascular biology.
My expertise is in application of model organisms, especially zebrafish (Danio rerio),
in biomedical research. These models can help to understand and solve
biomedical problems efficiently and ethically. Especially, when combined
with high-resolution intravital microscopy, these models can give deep
insights into developmental and disease processes in vivo. By using fish
eggs and embryos, it is also possible to reduce the number of more
complex and developed organisms used in research. These models, however, require certain set of skills and knowledge which is not part of the training of most medical and biomedical scientist. To facilite them to utilize the power of zebrafish models to advance their research, I have established a Zebrafish Core under Turku Centre for Biotechnology (University of Turku and Åbo Akademi University).
- Jnk1 and downstream signalling hubs regulate anxiety-like behaviours in a zebrafish larvae phenotypic screen (2024)
- Scientific Reports
- SIX2 promotes cell plasticity via Wnt/β-catenin signalling in androgen receptor independent prostate cancer (2024)
- Nucleic Acids Research
- TLNRD1 is a CCM complex component and regulates endothelial barrier integrity (2024)
- Journal of Cell Biology
- Effect of caldesmon mutations in the development of zebrafish embryos (2023)
- Biochemical and Biophysical Research Communications
- Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer (2023)
- Oncogenesis
- Impaired fin regeneration and angiogenesis in aged zebrafish and turquoise killifish (2023)
- Biology Open
- Modeling of Zebrafish Housing Temperatures During Power Outage and Instrument Failure (2023)
- Zebrafish
- PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers (2023)
- Molecular Oncology
- STAT5b is a key effector of NRG-1/ERBB4-mediated myocardial growth (2023)
- EMBO Reports
- Distinctive effects of SGLT2 inhibitors on angiogenesis in zebrafish embryos (2022)
- Biomedicine and Pharmacotherapy



