A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Imaging in focus: An introduction to denoising bioimages in the era of deep learning
Tekijät: Laine Romain F., Jacquemet Guillaume, Krull Alexander
Kustantaja: PERGAMON-ELSEVIER SCIENCE LTD
Julkaisuvuosi: 2021
Journal: International Journal of Biochemistry and Cell Biology
Tietokannassa oleva lehden nimi: INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Lehden akronyymi: INT J BIOCHEM CELL B
Artikkelin numero: 106077
Vuosikerta: 140
Sivujen määrä: 9
ISSN: 1357-2725
eISSN: 1878-5875
DOI: https://doi.org/10.1016/j.biocel.2021.106077
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/67531966
Fluorescence microscopy enables the direct observation of previously hidden dynamic processes of life, allowing profound insights into mechanisms of health and disease. However, imaging of live samples is fundamentally limited by the toxicity of the illuminating light and images are often acquired using low light conditions. As a consequence, images can become very noisy which severely complicates their interpretation. In recent years, deep learning (DL) has emerged as a very successful approach to remove this noise while retaining the useful signal. Unlike classical algorithms which use well-defined mathematical functions to remove noise, DL methods learn to denoise from example data, providing a powerful content-aware approach. In this review, we first describe the different types of noise that typically corrupt fluorescence microscopy images and introduce the denoising task. We then present the main DL-based denoising methods and their relative advantages and disadvantages. We aim to provide insights into how DL-based denoising methods operate and help users choose the most appropriate tools for their applications.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
