Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia



: Huuhka Milla, Turunen Aaro

Publisher: HINDAWI LTD

: 2021

: Case Reports in Dentistry

: CASE REPORTS IN DENTISTRY

: CASE REP DENT

: ARTN 5571649

: 2021

: 4

: 2090-6447

DOI: https://doi.org/10.1155/2021/5571649

: https://research.utu.fi/converis/portal/detail/Publication/66662508


Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.

Last updated on 2024-26-11 at 23:30