B1 Non-refereed article in a scientific journal
Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
Authors: Huuhka Milla, Turunen Aaro
Publisher: HINDAWI LTD
Publication year: 2021
Journal: Case Reports in Dentistry
Journal name in source: CASE REPORTS IN DENTISTRY
Journal acronym: CASE REP DENT
Article number: ARTN 5571649
Volume: 2021
Number of pages: 4
ISSN: 2090-6447
DOI: https://doi.org/10.1155/2021/5571649(external)
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/66662508(external)
Abstract
Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.
Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.
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