A1 Refereed original research article in a scientific journal

Socioeconomic Status and Access to Treatment in Diffuse Large B‐Cell Lymphoma;




AuthorsKuitunen, Joonas; Marin, Katja; Tokola, Susanna; Pollari, Marjukka; Jyrkkiö, Sirkku; Suominen, Minna; Partanen, Anu; Vuolukka, Kristiina; Sunela, Kaisa; Rönkä, Aino; Aromaa-Häyhä, Annikki; Klaavuniemi, Tuula; Hakalahti, Anna; Kuusisto, Milla E. L.; Kuitunen, Hanne; Kuittinen, Outi

PublisherWiley

Publication year2026

Journal: Cancer Medicine

Article numbere71920

Volume15

Issue5

eISSN2045-7634

DOIhttps://doi.org/10.1002/cam4.71920

Publication's open availability at the time of reportingOpen Access

Publication channel's open availability Open Access publication channel

Web address https://doi.org/10.1002/cam4.71920

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/523655373

Self-archived copy's licenceCC BY NC ND

Self-archived copy's versionPublisher`s PDF


Abstract

Background and purpose: Large B-cell lymphoma (LBCL) is the most common lymphoma subtype, with diffuse LBCL (DLBCL) accounting for 30%-40% of new lymphoma cases. The International Prognostic Index (IPI) is widely used for prognostic assessment in DLBCL. Clinical features associated with a poorer prognosis, such as advanced disease stage, could be a consequence of delayed diagnosis, which in turn may be influenced by a patient's socioeconomic status. While healthcare in Finland aims to ensure equal access to timely and high-quality treatment for all, disparities still exist. In this study we evaluated the impact of patients' socioeconomic status on their access to diagnostic procedures.

Patient/material and methods: Patient data was prospectively collected from seven hospitals between October 2014 and March 2020 in Finland. A total of 160 patients provided information regarding their diagnostic pathway and socioeconomic status via questionnaire. The data was combined with clinical data from patient records.

Results: The symptoms to treatment interval (STI) varied between age groups (p = 0.019), marital status groups (p = 0.023), and healthcare providers. In addition, age, income level, and occupational status (all p < 0.001) influenced which healthcare provider patients used as their first place of contact.

Interpretation: In this prospective study, we analyzed the impact of patients' socioeconomic status on treatment delays within the treatment pathway. Socioeconomic status was found to have a significant effect on these delays. The delays varied not only between different socioeconomic groups but also across different healthcare providers.

Keywords: delayed diagnosis; diffuse; health care disparities; health services accessibility; large B‐cell; lymphoma; socioeconomic factors.



Keywords:
delayed diagnosisdiffusehealth care disparitieslarge B-cell

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Funding information in the publication
This independent research was supported by Incyte International Sarl (Morges, Switzerland) through the supply of funding. Open access publishing facilitated by Ita-Suomen yliopisto, as part of the Wiley - FinELib agreement.


Last updated on 02/06/2026 01:39:01 PM