A1 Refereed original research article in a scientific journal
Socioeconomic Status and Access to Treatment in Diffuse Large B‐Cell Lymphoma; 
Authors: Kuitunen, Joonas; Marin, Katja; Tokola, Susanna; Pollari, Marjukka; Jyrkkiö, Sirkku; Suominen, Minna; Partanen, Anu; Vuolukka, Kristiina; Sunela, Kaisa; Rönkä, Aino; Aromaa-Häyhä, Annikki; Klaavuniemi, Tuula; Hakalahti, Anna; Kuusisto, Milla E. L.; Kuitunen, Hanne; Kuittinen, Outi
Publisher: Wiley
Publication year: 2026
Journal: Cancer Medicine
Article number: e71920
Volume: 15
Issue: 5
eISSN: 2045-7634
DOI: https://doi.org/10.1002/cam4.71920
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Open Access publication channel
Web address : https://doi.org/10.1002/cam4.71920
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/523655373
Self-archived copy's licence: CC BY NC ND
Self-archived copy's version: Publisher`s PDF
Background and purpose: Large B-cell lymphoma (LBCL) is the most common lymphoma subtype, with diffuse LBCL (DLBCL) accounting for 30%-40% of new lymphoma cases. The International Prognostic Index (IPI) is widely used for prognostic assessment in DLBCL. Clinical features associated with a poorer prognosis, such as advanced disease stage, could be a consequence of delayed diagnosis, which in turn may be influenced by a patient's socioeconomic status. While healthcare in Finland aims to ensure equal access to timely and high-quality treatment for all, disparities still exist. In this study we evaluated the impact of patients' socioeconomic status on their access to diagnostic procedures.
Patient/material and methods: Patient data was prospectively collected from seven hospitals between October 2014 and March 2020 in Finland. A total of 160 patients provided information regarding their diagnostic pathway and socioeconomic status via questionnaire. The data was combined with clinical data from patient records.
Results: The symptoms to treatment interval (STI) varied between age groups (p = 0.019), marital status groups (p = 0.023), and healthcare providers. In addition, age, income level, and occupational status (all p < 0.001) influenced which healthcare provider patients used as their first place of contact.
Interpretation: In this prospective study, we analyzed the impact of patients' socioeconomic status on treatment delays within the treatment pathway. Socioeconomic status was found to have a significant effect on these delays. The delays varied not only between different socioeconomic groups but also across different healthcare providers.
Keywords: delayed diagnosis; diffuse; health care disparities; health services accessibility; large B‐cell; lymphoma; socioeconomic factors.
Keywords:
delayed diagnosis, diffuse, health care disparities, large B-cell
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Funding information in the publication:
This independent research was supported by Incyte International Sarl (Morges, Switzerland) through the supply of funding. Open access publishing facilitated by Ita-Suomen yliopisto, as part of the Wiley - FinELib agreement.