A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
ONWARD: A one health, pan-European multidisciplinary network advancing surveillance, research, clinical management and control of zoonotic hepeviruses
Tekijät: Rivero-Juarez, Antonio; Velebit, Branko; Johne, Reimar; Abravanel, Florence; Reuter, Gabor; Dudman, Susanne; Kamar, Nassim; Jemersic, Lorena; di Bartolo, Ilaria; Hasanoglu, Imran; Anita, Adriana; Cook, Nigel; Ruta, Simona; Nauwelaers, Inne; Milojević, Lazar; Todorovska, Elena; Mojsova, Sandra; Zerja, Arjana; Avellon, Ana; Hakze-van der Honing, Renate; Harvala, Heli; Sao Jose Nascimento, Maria; Mesquita, Joao R.; members of ONWARD
Kustantaja: Elsevier
Julkaisuvuosi: 2026
Lehti: Journal of Clinical Virology
Artikkelin numero: 105944
Vuosikerta: 184
ISSN: 1386-6532
eISSN: 1873-5967
DOI: https://doi.org/10.1016/j.jcv.2026.105944
Julkaisun avoimuus kirjaamishetkellä: Avoimesti saatavilla
Julkaisukanavan avoimuus : Osittain avoin julkaisukanava
Verkko-osoite: https://doi.org/10.1016/j.jcv.2026.105944
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/523223464
Rinnakkaistallenteen lisenssi: CC BY NC
Rinnakkaistallennetun julkaisun versio: Kustantajan versio
Zoonotic hepeviruses, particularly hepatitis E virus (HEV, species Paslahepevirus balayani) represent a major yet underestimated public health challenge in Europe. Despite being the leading cause of acute viral hepatitis, surveillance, diagnostic practices and prevention strategies remain heterogeneous across EU/EEA countries, limiting comparability and hindering accurate burden estimates. Underdiagnosis is further compounded by extrahepatic manifestations and the growing impact of chronic HEV infection in immunocompromised patients. At the human–animal–environment interface, zoonotic HEV circulates widely in domestic pigs, wildlife and food products, while coordinated surveillance and control measures remain inconsistently implemented. The recent recognition of ratHEV (species Rocahepevirus ratti) as a cause of acute and chronic hepatitis in Europe further expands the spectrum of zoonotic hepevirus infections and underscores the need for integrated One Health approaches. To address these challenges, the One Health Zoonotic Hepevirus Network (ONWARD; COST Action CA24140) was launched in 2025 as a pan-European, multidisciplinary collaboration uniting experts across human, veterinary, food safety and environmental health sectors. ONWARD aims to harmonise diagnostic tools, strengthen clinical research, integrate multisectoral surveillance, promote capacity building and support evidence-based policy development. By fostering coordination with European stakeholders ONWARD provides a structured framework to strengthen preparedness, surveillance and response to zoonotic hepevirus threats across Europe.
Ladattava julkaisu This is an electronic reprint of the original article. |
Julkaisussa olevat rahoitustiedot:
This article is based upon work from COST Action CA24140 – ONWARD: One Health Zoonotic Hepevirus Network, supported by COST (European Cooperation in Science and Technology, www.cost.eu)