A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä

Mortality and causes of death after surgery for chronic subdural hematoma: a post hoc study of the FINISH randomized trial




TekijätTommiska, Pihla; Knuutinen, Oula; Lönnrot, Kimmo; Luoto, Teemu; Leinonen, Ville; Koivisto, Timo; Tetri, Sami; Posti, Jussi P.; Raj, Rahul; FINISH study group

KustantajaSpringer Nature

Julkaisuvuosi2025

Lehti: Acta Neurochirurgica

Artikkelin numero310

Vuosikerta167

ISSN0001-6268

eISSN0942-0940

DOIhttps://doi.org/10.1007/s00701-025-06728-9

Julkaisun avoimuus kirjaamishetkelläAvoimesti saatavilla

Julkaisukanavan avoimuus Kokonaan avoin julkaisukanava

Verkko-osoitehttps://doi.org/10.1007/s00701-025-06728-9

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/505792848


Tiivistelmä
Purpose

Chronic subdural hematoma (CSDH) is a common neurosurgical disease, especially prevalent among the elderly and is associated with reduced life expectancy. This study investigated mortality and causes of death after burr-hole drainage surgery for CSDH.

Methods

We included patients from the FINISH trial, a national, multicenter, randomized study conducted in Finland during 2020–2022. We obtained mortality data from Statistics Finland. For the classification of causes of death, we used the European shortlist of 86 causes, which is derived from the 10th revision of the International Classification of Diseases and Related Health Problems (ICD-10).

Results

Overall, the FINISH trial population included 589 patients (median age 78 years, 28% women). After a median follow-up of 16.4 months (IQR 9.7–23.1), 82 patients (14%) died. The median age at death was 85 years (IQR 81–89), and the median time from surgery to death was 6.5 months (IQR 2.4–15.3). The leading causes of death were circulatory diseases (34%), accidents (16%), and dementia (15%). A higher number of pre-existing comorbidities was significantly associated with increased mortality. In particular, dementia, cardiac arrhythmia, prior cerebrovascular events, and hypertension emerged as significant risk factors for death.

Conclusion

This study provides valuable insights into mortality rates and causes of death among patients undergoing CSDH surgery. The findings underscore the critical role of pre-existing comorbidities in influencing patient outcomes.


Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.




Julkaisussa olevat rahoitustiedot
Open access funded by Helsinki University Library. The FINISH trial was supported by the State Fund for University Level Health Research (Helsinki University Hospital), Finska Läkaresällskapet, Svenska Kulturfonden and Medicinska Understödsföreningen Liv & Hälsa. The funders had no role in the study design, in the collection, analysis, or interpretation of data, in the writing of the report, or in the decision to submit the paper for publication.


Last updated on 2025-10-12 at 13:38