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Flow-diverting stents for the treatment of unruptured distal anterior cerebral artery aneurysms: analysis of the CRETA Registry




TekijätScarcia, Luca; Clarencon, Frederic; Dmytriw, Adam A.; Shotar, Eimad; Premat, Kevin; Jabbour, Pascal; Tjoumakaris, Stavropoula, I; Gooch, Reid; Psychogios, Marios-Nikos; Ntoulias, Nikolaos; Sporns, Peter B.; Puri, Ajit S.; Singh, Jasmeet; Kuhn, Anna Luisa; Hassan, Ameer E.; Algin, Oktay; Moehlenbruch, Markus A.; Hohenstatt, Sophia; Russo, Riccardo; Bergui, Mauro; Goren, Oded; Kole, Matthew J.; Bankole, Nourou Dine Adeniran; Bibi, Richard; Boulouis, Gregoire; Morimoto, Takeshi; Sakakibara, Fumihiro; Pop, Raoul; Juravle, Ciprian; Ho, Joanna W. K.; Ferrario, Angel; Pujol Lereis, Virginia; Cooper, Jared; Gandhi, Chirag D.; Salsano, Giancarlo; Castellan, Lucio; Camilli, Arianna; Consoli, Arturo; Sgreccia, Alessandro; Raz, Eytan; Chung, Charlotte; Burel, Julien; Papagiannaki, Chrysanthi; Rasheed, Umair; Baqir Hassan, Khawaja Muhammad; Hong, Tao; Ji, Zhe; Rautio, Riitta; Sinisalo, Matias; Ruggiero, Maria; Lafe, Elvis; Da Ros, Valerio; Bellini, Luigi; Gabrieli, Joseph D.; Cester, Giacomo; Levitt, Michael R.; Carroll, Kate T.; Abecassis, Zack A.; Caragliano, Antonio Armando; Vinci, Sergio L.; Bellanger, Guillaume; Cognard, Christophe; Marnat, Gaultier; Saleille, Lisa; Limbucci, Nicola; Capasso, Francesco; Piano, Mariangela; Rollo, Claudia; Guedon, Alexis; Arpaia, Francesco; Romi, Andrea; Di Caterino, Fortunato; Biondi, Alessandra; Kalsoum, Erwah; Mykola, Vyval; Guenego, Adrien; Patel, Aman B.; Pereira, Vitor M.; Pedicelli, Alessandro; Alexandre, Andrea Maria; CRETA investigators

KustantajaBMJ PUBLISHING GROUP

KustannuspaikkaLONDON

Julkaisuvuosi2025

JournalJournal of NeuroInterventional Surgery

Tietokannassa oleva lehden nimiJOURNAL OF NEUROINTERVENTIONAL SURGERY

Lehden akronyymiJ NEUROINTERV SURG

Sivujen määrä7

ISSN1759-8478

eISSN1759-8486

DOIhttps://doi.org/10.1136/jnis-2024-022315

Verkko-osoitehttps://doi.org/10.1136/jnis-2024-022315


Tiivistelmä

Background: Data about the safety and the efficacy of flow diversion for distal anterior cerebral artery (DACA) aneurysms are limited. We present the largest multicenter analysis evaluating the outcomes of flow diversion in unruptured DACA aneurysm treatment.

Methods: Databases from 39 centers were retrospectively reviewed for unruptured DACA aneurysms treated with flow-diverting stents. Demographics, clinical presentation, radiographic characteristics, procedural complications, and outcomes were assessed.

Results: A total of 168 patients with 168 unruptured DACA aneurysms were treated between January 2018 and December 2022. One hundred and twenty-five were women (74.4%) and the median age was 61 (IQR 52-67) years. The most common morphology was saccular (91.7%), with branch involvement in 61.9% of cases. Median parent vessel diameter was 1.9 mm (IQR 1.7-2.2) and stents were successfully deployed in 99.4% of cases. In 96.4% a single stent was implanted, while 3.6% of cases required two stents. Median imaging follow-up was 16.5 (IQR 7-24) months. At last follow-up the rate of occlusion (O'Kelly-Marotta scale C or D) was 82.1%. Symptomatic thromboembolic or hemorrhagic complications occurred in 5.3% of patients and the mortality rate was 0.6%. The rate of retreatment was 1.2%.

Conclusions: Flow-diverting stents are a reasonably safe and effective treatment option for unruptured DACA aneurysms.

Keywords: Aneurysm; Angiogra


Julkaisussa olevat rahoitustiedot
The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.


Last updated on 2025-06-05 at 17:17