A1 Refereed original research article in a scientific journal
Flow-diverting stents for the treatment of unruptured distal anterior cerebral artery aneurysms: analysis of the CRETA Registry
Authors: Scarcia, Luca; Clarencon, Frederic; Dmytriw, Adam A.; Shotar, Eimad; Premat, Kevin; Jabbour, Pascal; Tjoumakaris, Stavropoula, I; Gooch, Reid; Psychogios, Marios-Nikos; Ntoulias, Nikolaos; Sporns, Peter B.; Puri, Ajit S.; Singh, Jasmeet; Kuhn, Anna Luisa; Hassan, Ameer E.; Algin, Oktay; Moehlenbruch, Markus A.; Hohenstatt, Sophia; Russo, Riccardo; Bergui, Mauro; Goren, Oded; Kole, Matthew J.; Bankole, Nourou Dine Adeniran; Bibi, Richard; Boulouis, Gregoire; Morimoto, Takeshi; Sakakibara, Fumihiro; Pop, Raoul; Juravle, Ciprian; Ho, Joanna W. K.; Ferrario, Angel; Pujol Lereis, Virginia; Cooper, Jared; Gandhi, Chirag D.; Salsano, Giancarlo; Castellan, Lucio; Camilli, Arianna; Consoli, Arturo; Sgreccia, Alessandro; Raz, Eytan; Chung, Charlotte; Burel, Julien; Papagiannaki, Chrysanthi; Rasheed, Umair; Baqir Hassan, Khawaja Muhammad; Hong, Tao; Ji, Zhe; Rautio, Riitta; Sinisalo, Matias; Ruggiero, Maria; Lafe, Elvis; Da Ros, Valerio; Bellini, Luigi; Gabrieli, Joseph D.; Cester, Giacomo; Levitt, Michael R.; Carroll, Kate T.; Abecassis, Zack A.; Caragliano, Antonio Armando; Vinci, Sergio L.; Bellanger, Guillaume; Cognard, Christophe; Marnat, Gaultier; Saleille, Lisa; Limbucci, Nicola; Capasso, Francesco; Piano, Mariangela; Rollo, Claudia; Guedon, Alexis; Arpaia, Francesco; Romi, Andrea; Di Caterino, Fortunato; Biondi, Alessandra; Kalsoum, Erwah; Mykola, Vyval; Guenego, Adrien; Patel, Aman B.; Pereira, Vitor M.; Pedicelli, Alessandro; Alexandre, Andrea Maria; CRETA investigators
Publisher: BMJ PUBLISHING GROUP
Publishing place: LONDON
Publication year: 2025
Journal: Journal of NeuroInterventional Surgery
Journal name in source: JOURNAL OF NEUROINTERVENTIONAL SURGERY
Journal acronym: J NEUROINTERV SURG
Number of pages: 7
ISSN: 1759-8478
eISSN: 1759-8486
DOI: https://doi.org/10.1136/jnis-2024-022315
Web address : https://doi.org/10.1136/jnis-2024-022315
Background: Data about the safety and the efficacy of flow diversion for distal anterior cerebral artery (DACA) aneurysms are limited. We present the largest multicenter analysis evaluating the outcomes of flow diversion in unruptured DACA aneurysm treatment.
Methods: Databases from 39 centers were retrospectively reviewed for unruptured DACA aneurysms treated with flow-diverting stents. Demographics, clinical presentation, radiographic characteristics, procedural complications, and outcomes were assessed.
Results: A total of 168 patients with 168 unruptured DACA aneurysms were treated between January 2018 and December 2022. One hundred and twenty-five were women (74.4%) and the median age was 61 (IQR 52-67) years. The most common morphology was saccular (91.7%), with branch involvement in 61.9% of cases. Median parent vessel diameter was 1.9 mm (IQR 1.7-2.2) and stents were successfully deployed in 99.4% of cases. In 96.4% a single stent was implanted, while 3.6% of cases required two stents. Median imaging follow-up was 16.5 (IQR 7-24) months. At last follow-up the rate of occlusion (O'Kelly-Marotta scale C or D) was 82.1%. Symptomatic thromboembolic or hemorrhagic complications occurred in 5.3% of patients and the mortality rate was 0.6%. The rate of retreatment was 1.2%.
Conclusions: Flow-diverting stents are a reasonably safe and effective treatment option for unruptured DACA aneurysms.
Keywords: Aneurysm; Angiogra
Funding information in the publication:
The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
