A2 Refereed review article in a scientific journal
Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans
Authors: Belibasakis GN, Maula T, Bao K, Lindholm M, Bostanci N, Oscarsson J, Ihalin R, Johansson A
Publisher: MDPI
Publication year: 2019
Journal: Pathogens
Journal name in source: Pathogens (Basel, Switzerland)
Journal acronym: Pathogens
Article number: E222
Volume: 8
Issue: 4
Number of pages: 23
ISSN: 2076-0817
eISSN: 2076-0817
DOI: https://doi.org/10.3390/pathogens8040222
Web address : https://www.mdpi.com/2076-0817/8/4/222
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/42910627
Aggregatibacter actinomycetemcomitans is a periodontal pathogen
colonizing the oral cavity of a large proportion of the human
population. It is equipped with several potent virulence factors that
can cause cell death and induce or evade inflammation. Because of the
large genetic diversity within the species, both harmless and highly
virulent genotypes of the bacterium have emerged. The oral condition and
age, as well as the geographic origin of the individual, influence the
risk to be colonized by a virulent genotype of the bacterium. In the
present review, the virulence and pathogenicity properties of A. actinomycetemcomitans will be addressed.
Downloadable publication This is an electronic reprint of the original article. |  |
